[HTML][HTML] Ocular benzalkonium chloride exposure: problems and solutions
MH Goldstein, FQ Silva, N Blender, T Tran, S Vantipalli - Eye, 2022 - nature.com
Preservatives in multidose formulations of topical ophthalmic medications are crucial for
maintaining sterility but can be toxic to the ocular surface. Benzalkonium chloride (BAK) …
maintaining sterility but can be toxic to the ocular surface. Benzalkonium chloride (BAK) …
[HTML][HTML] Topical glaucoma medications–clinical implications for the ocular surface
Glaucoma is a leading cause of irreversible blindness. The use of topical eye drops to
reduce intraocular pressure remains the mainstay treatment. These eye drops frequently …
reduce intraocular pressure remains the mainstay treatment. These eye drops frequently …
The molecular aspect of anti-glaucomatous eye drops-are we harming our patients?
A Hedengran, M Kolko - Molecular Aspects of Medicine, 2023 - Elsevier
Glaucoma is one of the leading causes of irreversible blindness. Progression is halted with a
reduction in intraocular pressure (IOP), which is most often achieved with eye drops. A major …
reduction in intraocular pressure (IOP), which is most often achieved with eye drops. A major …
[HTML][HTML] Ocular surface disease: a known yet overlooked side effect of topical glaucoma therapy
Ocular surface disease (OSD), a disorder affecting the lacrimal and meibomian glands and
the corneal and conjunctival epithelium, is a well-known complication of topical glaucoma …
the corneal and conjunctival epithelium, is a well-known complication of topical glaucoma …
Glaucoma and dry eye disease: Opportunity to assess and treat
LM Nijm, J Schweitzer… - Clinical Ophthalmology, 2023 - Taylor & Francis
Dry eye disease (DED) has been found to occur at a higher prevalence in individuals with
glaucoma than in individuals without glaucoma. The relationship between glaucoma and …
glaucoma than in individuals without glaucoma. The relationship between glaucoma and …
The role of trabeculectomy in the era of minimally invasive glaucoma surgery
S Kalarn, T Le, DJ Rhee - Current Opinion in Ophthalmology, 2022 - journals.lww.com
Patients with glaucoma greatly benefit from combining cataract surgery with a MIGS
procedure that can be tailored to disease severity and medication use. Certain MIGS …
procedure that can be tailored to disease severity and medication use. Certain MIGS …
Current progress in preservative-free topical ophthalmic formulations
Ophthalmic formulations have enormous applications in treating several ocular disorders.
Principally, the ocular formulations must be sterile. Hence, preservatives are conventionally …
Principally, the ocular formulations must be sterile. Hence, preservatives are conventionally …
[HTML][HTML] Surgical results of trabeculectomy among groups stratified by prostaglandin-associated periorbitopathy severity
A Ishida, T Miki, T Naito, S Ichioka, Y Takayanagi… - Ophthalmology, 2023 - Elsevier
Purpose To report the role of prostaglandin-associated periorbitopathy (PAP) severity in the
surgical effectiveness of trabeculectomy (LEC). Design Retrospective observational case …
surgical effectiveness of trabeculectomy (LEC). Design Retrospective observational case …
[HTML][HTML] Impact of dorzolamide, benzalkonium-preserved dorzolamide and benzalkonium-preserved brinzolamide on selected biomarkers of oxidative stress in the …
L Sedlak, M Świerczyńska, W Borymska, M Zych… - BMC …, 2021 - Springer
Background Long-term use of topical, especially benzalkonium chloride (BAC)-preserved,
antiglaucoma medications can cause a negative impact on the ocular surface. The aim of …
antiglaucoma medications can cause a negative impact on the ocular surface. The aim of …
Generic benzalkonium chloride‐preserved travoprost eye drops are not identical to the branded polyquarternium‐1‐preserved travoprost eye drop: Effect on cultured …
A Hedengran, JC Freiberg, PM Hansen… - Acta …, 2022 - Wiley Online Library
Purpose To investigate the effect of polyquaternium‐1 (PQ)‐preserved and benzalkonium
chloride (BAK)‐preserved travoprost eye drops on viability of primary human conjunctival …
chloride (BAK)‐preserved travoprost eye drops on viability of primary human conjunctival …