Immunotherapy in ovarian cancer

GM Mantia-Smaldone, B Corr… - Human vaccines & …, 2012 - Taylor & Francis
Ovarian cancer is the most deadly gynecologic malignancy, with more than 15,000 deaths
anticipated in 2012.1 While approximately 80% of patients will respond to frontline …

Clinical radioimmunotherapy—the role of radiobiology

JP Pouget, I Navarro-Teulon, M Bardiès… - Nature reviews Clinical …, 2011 - nature.com
Conventional external-beam radiation therapy is dedicated to the treatment of localized
disease, whereas radioimmunotherapy represents an innovative tool for the treatment of …

[PDF][PDF] Relationships between tumor size and curability for uniformly targeted therapy with beta-emitting radionuclides

JA O'donoghue, M Bardies… - Journal of Nuclear …, 1995 - Soc Nuclear Med
Absorbed fractions (@) were calculated for spheres that ranged in diameter from 20@ mto
4.4 cm. The details of the computa tional procedure used have been reported elsewhere (8) …

[HTML][HTML] Therapeutic radionuclides in nuclear medicine: current and future prospects

CH Yeong, M Cheng, KH Ng - Journal of Zhejiang University …, 2014 - ncbi.nlm.nih.gov
The potential use of radionuclides in therapy has been recognized for many decades. A
number of radionuclides, such as iodine-131 (131 I), phosphorous-32 (32 P), strontium-90 …

Cellular mucins: targets for immunotherapy

V Apostolopoulos, IFC McKenzie - Critical Reviews™ in …, 1994 - dl.begellhouse.com
Mucins are attracting great interest as potential targets for immunotherapy in the
development of vaccines for cancers expressing Mucinl (MUC1)(eg, breast, pancreas, ovary …

Pharmacokinetics and Imaging of 212Pb-TCMC-Trastuzumab After Intraperitoneal Administration in Ovarian Cancer Patients

RF Meredith, J Torgue, MT Azure, S Shen… - Cancer Biotherapy …, 2014 - liebertpub.com
Purpose: Study distribution, pharmacokinetics, and safety of intraperitoneal (IP) 212Pb-
TCMC-trastuzumab in patients with HER-2-expressing malignancy. Experimental Design: IP …

MUC1: a target molecule for cancer therapy

R Singh, D Bandyopadhyay - Cancer biology & therapy, 2007 - Taylor & Francis
MUC1 is a mucin family protein, overexpressed in more than 90% of breast cancers in an
underglycosylated form, exposing the core peptides of the extracellular domain that act as a …

Radioimmunotherapy of interleukin-2R alpha-expressing adult T-cell leukemia with Yttrium-90-labeled anti-Tac [see comments]

TA Waldmann, JD White, JA Carrasquillo, JC Reynolds… - 1995 - ashpublications.org
Adult T-cell leukemia (ATL) is a malignancy of mature lymphocytes caused by the retrovirus
human T-cell lymphotropic virus-I. It is an aggressive leukemia with a median survival time of …

Phase III trial of intraperitoneal therapy with yttrium-90–labeled HMFG1 murine monoclonal antibody in patients with epithelial ovarian cancer after a surgically defined …

RH Verheijen, LF Massuger, BB Benigno… - Journal of clinical …, 2006 - ascopubs.org
Purpose This was a multinational, open-label, randomized phase III trial comparing yttrium-
90–labeled murine HMFG1 (90Y-muHMFG1) plus standard treatment versus standard …

Ovarian cancer.

JS Berek, RCJ Bast - Hacker &Amp, 1985 - books.google.com
Ovarian cancer is the fifth most common cancer among females in the United States,
accounting for one fourth of all gynecologic cancers. It is the leading cause of death from …