In developmental biology, knowledge of cell structure and their (morpho) dynamic behavior,
leads to a comprehensive understanding of their conducts and the mechanisms in which …

Label-free imaging uses inherent contrast mechanisms within cells to create image contrast
without introducing dyes/labels, which may confound results. Quantitative phase imaging is …

We present TrackMate, an open source Fiji plugin for the automated, semi-automated, and
manual tracking of single-particles. It offers a versatile and modular solution that works out of …

Ageing impairs tissue repair. This defect is pronounced in skeletal muscle, whose
regeneration by muscle stem cells (MuSCs) is robust in young-adult animals, but inefficient …

Stain-free, single-cell segmentation and tracking is tantamount to the holy grail of
microscopic cell migration analysis. Phase contrast microscopy (PCM) images with cells at …

The ability of cells to migrate is a fundamental physiological process involved in embryonic
development, tissue homeostasis, immune surveillance, and wound healing. Therefore, the …

Glioblastoma (GBM) is the most malignant and highly aggressive brain tumor. In this study,
four types of typical GBM cell lines (LN229, SNB19, U87, U251) were cultured in a …

Motivation: Time-lapse experiments play a key role in studying the dynamic behavior of
cells. Single-cell tracking is one of the fundamental tools for such analyses. The vast majority …

Cell migration is central to the development and maintenance of multicellular organisms.
Fundamental understanding of cell migration can, for example, direct novel therapeutic …

Integrins are cellular receptors that bind the extracellular matrix (ECM) and facilitate the
transduction of biochemical and biophysical microenvironment cues into cellular responses …