Dendrite morphogenesis is a complex but well-orchestrated process and includes the
development of dendritic branches, forming characteristic dendrite arbors, and dendritic …

Neural connectivity requires proper polarization of neurons, guidance to appropriate target
locations, and establishment of synaptic connections. From when neurons are born to when …

Glioblastoma are heterogeneous tumors composed of highly invasive and highly
proliferative clones. Heterogeneity in invasiveness could emerge from discrete biophysical …

Dynamic control of the actin and microtubule cytoskeletons underlie nearly every critical
process during neural development, and requires multiple dimensions of regulation …

The brain synthesizes a variety of neurosteroids, including neuroestradiol. Inhibition of
neuroestradiol synthesis results in alterations in basic neurodevelopmental processes, such …

Several X-linked genes are involved in neuronal differentiation and may contribute to the
generation of sex dimorphisms in the brain. Previous results showed that XX hypothalamic …

Cell biologists generally consider that microtubules and actin play complementary roles in
long-and short-distance transport in animal cells. On the contrary, using melanosomes of …

Almost 25 years have passed since a mutation of a formin gene, DIAPH1, was identified as
being responsible for a human inherited disorder: a form of sensorineural hearing loss …

The obligate intracellular pathogen Chlamydia trachomatis manipulates the host actin
cytoskeleton to assemble actin-rich structures that drive pathogen entry. The recent …

Since its discovery in Drosophila, the Notch signaling pathway has been studied in
numerous developmental contexts in diverse multicellular organisms. The role of Notch …