Halogen bonding: an underestimated player in membrane–ligand interactions
Halogen bonds (XBs) are noncovalent interactions where halogen atoms act as electrophilic
species interacting with Lewis bases. These interactions are relevant in biochemical …
species interacting with Lewis bases. These interactions are relevant in biochemical …
[HTML][HTML] Dissecting the chloride–nitrate anion transport assay
A systematic study of chloride vs. nitrate selectivity across six anion transporters has
revealed a good correlation between the selectivities of their anion binding and membrane …
revealed a good correlation between the selectivities of their anion binding and membrane …
[HTML][HTML] Full elucidation of the transmembrane anion transport mechanism of squaramides using in silico investigations
I Marques, PMR Costa, MQ Miranda… - Physical Chemistry …, 2018 - pubs.rsc.org
A comprehensive experimental and theoretical investigation of the transmembrane chloride
transport promoted by four series of squaramide derivatives, with different degrees of …
transport promoted by four series of squaramide derivatives, with different degrees of …
[HTML][HTML] Synthesis and anion binding studies of tris (3-aminopropyl) amine-based tripodal urea and thiourea receptors: proton transfer-induced selectivity for hydrogen …
ME Khansari, CR Johnson, I Basaran, A Nafis… - RSC …, 2015 - pubs.rsc.org
Tris (3-aminopropyl) amine-based tripodal urea and thiourea receptors, tris ([(4-
cyanophenyl) amino] propyl) urea (L1) and tris ([(4-cyanophenyl) amino] propyl) thiourea …
cyanophenyl) amino] propyl) urea (L1) and tris ([(4-cyanophenyl) amino] propyl) thiourea …
Tilting and Tumbling in Transmembrane Anion Carriers: Activity Tuning through n‐Alkyl Substitution
SJ Edwards, I Marques, CM Dias… - … A European Journal, 2016 - Wiley Online Library
Anion transport by synthetic carriers (anionophores) holds promise for medical applications,
especially the treatment of cystic fibrosis. Among the factors which determine carrier activity …
especially the treatment of cystic fibrosis. Among the factors which determine carrier activity …
[HTML][HTML] Remarkable hexafunctional anion receptor with operational urea-based inner cleft and thiourea-based outer cleft: Novel design with high-efficiency for sulfate …
ME Khansari, A Mirchi, A Pramanik, CR Johnson… - Scientific …, 2017 - ncbi.nlm.nih.gov
The recognition of anions by designed receptors has attracted much attention in recent days.
In particular, the selective binding of sulfate with artificial receptors is important because of …
In particular, the selective binding of sulfate with artificial receptors is important because of …
Tripodal squaramide conjugates as highly effective transmembrane anion transporters
XJ Cai, Z Li, WH Chen - Bioorganic & Medicinal Chemistry Letters, 2017 - Elsevier
Two tripodal squaramide conjugates having 4-(trifluoromethyl) phenyl and 3, 5-bis
(trifluoromethyl) phenyl substituents were synthesized and found to exhibit highly efficient …
(trifluoromethyl) phenyl substituents were synthesized and found to exhibit highly efficient …
[HTML][HTML] Tripodal, Squaramide-Based Ion Pair Receptor for Effective Extraction of Sulfate Salt
D Jagleniec, M Wilczek, J Romański - Molecules, 2021 - mdpi.com
Combining three features—the high affinity of squaramides toward anions, cooperation in
ion pair binding and preorganization of the binding domains in the tripodal platform—led to …
ion pair binding and preorganization of the binding domains in the tripodal platform—led to …
Does lipophilicity affect the effectiveness of a transmembrane anion transporter? Insight from squaramido-functionalized bis (choloyl) conjugates
Z Li, LQ Deng, JX Chen, CQ Zhou… - Organic & Biomolecular …, 2015 - pubs.rsc.org
Six squaramido-functionalized bis (choloyl) conjugates were synthesized and fully
characterized on the basis of NMR (1H and 13C) and ESI MS (LR and HR) data. Their …
characterized on the basis of NMR (1H and 13C) and ESI MS (LR and HR) data. Their …
Synthesis, anion recognition, and transmembrane anionophoric activity of tripodal diaminocholoyl conjugates
Z Li, XH Yu, Y Chen, DQ Yuan… - The Journal of Organic …, 2017 - ACS Publications
In this paper, we present the synthesis, anion recognition, and anionophoric activity of 1, 3, 5-
tris (aminomethyl)-2, 4, 6-triethylbenzene-based tripodal 3α-hydroxy-7α, 12α-diamino-5β …
tris (aminomethyl)-2, 4, 6-triethylbenzene-based tripodal 3α-hydroxy-7α, 12α-diamino-5β …