A calcium-relay mechanism in vertebrate phototransduction
KW Koch, D Dell'Orco - ACS chemical neuroscience, 2013 - ACS Publications
Calcium-signaling in cells requires a fine-tuned system of calcium-transport proteins
involving ion channels, exchangers, and ion-pumps but also calcium-sensor proteins and …
involving ion channels, exchangers, and ion-pumps but also calcium-sensor proteins and …
The binding properties and physiological functions of recoverin
J Zang, SCF Neuhauss - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Recoverin (Rcv) is a low molecular-weight, neuronal calcium sensor (NCS) primarily located
in photoreceptor outer segments of the vertebrate retina. Calcium ions (Ca2+)-bound Rcv …
in photoreceptor outer segments of the vertebrate retina. Calcium ions (Ca2+)-bound Rcv …
Highly sensitive olfactory biosensors for the detection of volatile organic compounds by surface plasmon resonance imaging
Nowadays, monitoring of volatile organic compounds (VOCs) is very important in various
domains. In this work, we aimed to develop sensitive olfactory biosensors using odorant …
domains. In this work, we aimed to develop sensitive olfactory biosensors using odorant …
Negative SPR signals during low molecular weight analyte recognition
H Bonnet, L Coche-Guérente, E Defrancq… - Analytical …, 2021 - ACS Publications
Surface plasmon resonance (SPR) is a powerful technique for studying biomolecular
interactions mainly due to its sensitivity and real-time and label free advantages. While SPR …
interactions mainly due to its sensitivity and real-time and label free advantages. While SPR …
Biochemical and biophysical characterization of a plant calmodulin: Role of the N-and C-lobes in calcium binding, conformational change, and target interaction
In plants, transient elevation of intracellular Ca 2+ concentration in response to abiotic stress
is responsible for glutamate decarboxylase (GAD) activation via association with calmodulin …
is responsible for glutamate decarboxylase (GAD) activation via association with calmodulin …
Allosteric communication pathways routed by Ca2+/Mg2+ exchange in GCAP1 selectively switch target regulation modes
V Marino, D Dell'Orco - Scientific reports, 2016 - nature.com
GCAP1 is a neuronal calcium sensor protein that regulates the phototransduction cascade
in vertebrates by switching between activator and inhibitor of the target guanylate cyclase …
in vertebrates by switching between activator and inhibitor of the target guanylate cyclase …
A novel p.(Glu111Val) missense mutation in GUCA1A associated with cone-rod dystrophy leads to impaired calcium sensing and perturbed second messenger …
V Marino, G Dal Cortivo, E Oppici… - Human Molecular …, 2018 - academic.oup.com
Abstract Guanylate Cyclase-Activating Protein 1 (GCAP1) regulates the enzymatic activity of
the photoreceptor guanylate cyclases (GC), leading to inhibition or activation of the cyclic …
the photoreceptor guanylate cyclases (GC), leading to inhibition or activation of the cyclic …
Combining plasmonic and electrochemical biosensing methods
E Hemmerová, J Homola - Biosensors and Bioelectronics, 2024 - Elsevier
The idea of combining electrochemical (EC) and plasmonic biosensor methods was
introduced almost thirty years ago and the potential of electrochemical-plasmonic (EC-P) …
introduced almost thirty years ago and the potential of electrochemical-plasmonic (EC-P) …
Do conformational changes contribute to the surface plasmon resonance signal?
D Dobrovodský, C Di Primo - Biosensors and Bioelectronics, 2023 - Elsevier
Surface plasmon resonance (SPR)-based biosensors are widely used instruments for
characterizing molecular interactions. In theory the SPR signal depends only on mass …
characterizing molecular interactions. In theory the SPR signal depends only on mass …
Two retinal dystrophy-associated missense mutations in GUCA1A with distinct molecular properties result in a similar aberrant regulation of the retinal guanylate …
Two recently identified missense mutations (p. L84F and p. I107T) in GUCA1A, the gene
coding for guanylate cyclase (GC)-activating protein 1 (GCAP1), lead to a phenotype …
coding for guanylate cyclase (GC)-activating protein 1 (GCAP1), lead to a phenotype …