Epigenetic biomarkers and preterm birth
Preterm birth (PTB) is a major public health challenge, and novel, sensitive approaches to
predict PTB are still evolving. Epigenomic markers are being explored as biomarkers of PTB …
predict PTB are still evolving. Epigenomic markers are being explored as biomarkers of PTB …
The one-carbon metabolism as an underlying pathway for placental DNA methylation–a systematic review
MM van Vliet, S Schoenmakers, J Gribnau… - Epigenetics, 2024 - Taylor & Francis
Epigenetic modifications, including DNA methylation, are proposed mechanisms explaining
the impact of parental exposures to foetal development and lifelong health. Micronutrients …
the impact of parental exposures to foetal development and lifelong health. Micronutrients …
METTL3-Mediated m6A RNA Methylation of ZBTB4 Interferes With Trophoblast Invasion and Maybe Involved in RSA
N Huang, Y Gao, M Zhang, L Guo, L Qin… - Frontiers in Cell and …, 2022 - frontiersin.org
N6-methyladenosine (m6A) was the most abundant modification of mRNA and lncRNA in
mammalian cells and played an important role in many biological processes. However …
mammalian cells and played an important role in many biological processes. However …
Correlation of methylation status in MTHFR promoter region with recurrent pregnancy loss
MM Shaker, TA Shalabi, K Amr - Journal of Genetic Engineering and …, 2021 - Springer
Background DNA methylation is an epigenetic process for modifying transcription factors in
various genes. Methylenetetrahydrofolate reductase (MTHFR) stimulates synthesis of methyl …
various genes. Methylenetetrahydrofolate reductase (MTHFR) stimulates synthesis of methyl …
Emerging role of toll-like receptors signaling and its regulators in preterm birth: a narrative review
G Huang, D Yao, X Yan, M Zheng, P Yan… - Archives of Gynecology …, 2023 - Springer
Introduction Despite intensive research, preterm birth (PTB) rates have not decreased
significantly in recent years due to a lack of understanding of the underlying causes and …
significantly in recent years due to a lack of understanding of the underlying causes and …
A narrative review on the role of folate-mediated one-carbon metabolism and its associated gene polymorphisms in posing risk to preeclampsia
Preeclampsia (PE) presents a major obstetrical problem for mother and fetus which is
characterized by the onset of hypertension and proteinuria in formerly normotensive women …
characterized by the onset of hypertension and proteinuria in formerly normotensive women …
Integrative sperm DNA methylation and miRomics analysis highlights interaction of two epigenetic patterns of pseudomale inheritance in teleost
N Zhao, L Jia, L Chen, J Lin, Z Dong… - Frontiers in Marine …, 2022 - frontiersin.org
Proper DNA methylation in spermatozoa is essential for the normal development of fertilized
embryos through gene expression regulation. Abnormal sperm DNA methylation is …
embryos through gene expression regulation. Abnormal sperm DNA methylation is …
Causes of preterm birth: Genetic factors in preterm birth and preterm infant phenotypes
S Dauengauer‐Kirlienė, I Domarkienė… - Journal of Obstetrics …, 2023 - Wiley Online Library
Aim The aim is to provide an overview of recent research on genetic factors that influence
preterm birth in the context of neonatal phenotypic assessment. Methods This is a …
preterm birth in the context of neonatal phenotypic assessment. Methods This is a …
Maternal vitamin D deficiency increases the thromboxane/prostacyclin ratio through alterations in the one‐carbon cycle in Wistar rats
AA Nandi, NS Wadhwani, SR Joshi - BioFactors, 2019 - Wiley Online Library
This study aims to test the hypothesis that vitamin D deficiency can influence long‐chain
polyunsaturated fatty acid metabolism through alterations in the one‐carbon cycle. Wistar …
polyunsaturated fatty acid metabolism through alterations in the one‐carbon cycle. Wistar …
Pathoepigenetics: the role of epigenetic biomarkers in disease pathogenesis
R Cacabelos - Pharmacoepigenetics, 2019 - Elsevier
Pathoepigenetics refers to the role that alterations in the epigenetic machinery exert on
human disease. Over 80% of complex disorders (cardiovascular, cerebral, metabolic …
human disease. Over 80% of complex disorders (cardiovascular, cerebral, metabolic …