The clinical significance of duration of untreated psychosis: an umbrella review and random‐effects meta‐analysis
OD Howes, T Whitehurst, E Shatalina… - World …, 2021 - Wiley Online Library
The idea that a longer duration of untreated psychosis (DUP) leads to poorer outcomes has
contributed to extensive changes in mental health services worldwide and has attracted …
contributed to extensive changes in mental health services worldwide and has attracted …
Sex differences in schizophrenia relevant to clinical care
MV Seeman - Expert review of neurotherapeutics, 2021 - Taylor & Francis
Introduction: Most medical diagnoses present somewhat differently in men and women,
more so at specific periods of life. Treatment effects may also differ. This is true for …
more so at specific periods of life. Treatment effects may also differ. This is true for …
The course of general cognitive ability in individuals with psychotic disorders
K Jonas, W Lian, J Callahan, CJ Ruggero… - JAMA …, 2022 - jamanetwork.com
Importance Schizophrenia is associated with major cognitive deficits and has been
conceptualized as both a neurodevelopmental and a neurodegenerative disorder. However …
conceptualized as both a neurodevelopmental and a neurodegenerative disorder. However …
20-year prospective, sequential follow-up study of heterogeneity in associations of duration of untreated psychosis with symptoms, functioning, and quality of life …
D O'Keeffe, A Kinsella… - American Journal of …, 2022 - Am Psychiatric Assoc
Objective: Determining the extent to which relationships between duration of untreated
psychosis (DUP) and outcome endure longitudinally across the lifetime course of psychotic …
psychosis (DUP) and outcome endure longitudinally across the lifetime course of psychotic …
The pharmacologic treatment of schizophrenia—2021
DC Goff - Jama, 2021 - jamanetwork.com
Schizophrenia is a chronic psychotic disorder with typical onset in early adulthood and a
lifetime prevalence of approximately 1%. In addition to the hallmark symptoms of psychosis …
lifetime prevalence of approximately 1%. In addition to the hallmark symptoms of psychosis …
Long-term outcomes of first-admission psychosis: a naturalistic 21-year follow-up study of symptomatic, functional and personal recovery and their baseline predictors
V Peralta, E García de Jalón, L Moreno-Izco… - Schizophrenia …, 2022 - academic.oup.com
This study was aimed at characterizing long-term outcomes of first-admission psychosis and
examining their baseline predictors. Participants were assessed at baseline for 38 candidate …
examining their baseline predictors. Participants were assessed at baseline for 38 candidate …
What is the duration of untreated psychosis worldwide?–A meta-analysis of pooled mean and median time and regional trends and other correlates across 369 …
Duration of untreated psychosis (DUP) has been associated with poor mental health
outcomes. We aimed to meta-analytically estimate the mean and median DUP worldwide …
outcomes. We aimed to meta-analytically estimate the mean and median DUP worldwide …
What can psychiatrists learn from SARS and MERS outbreaks?
IE Sommer, PR Bakker - The Lancet Psychiatry, 2020 - thelancet.com
While standard care for patients with psychiatric disorders must continue during the current
COVID-19 pandemic, psychiatrists also need to treat psychiatric complications of patients …
COVID-19 pandemic, psychiatrists also need to treat psychiatric complications of patients …
Hippocampal volume in early psychosis: a 2-year longitudinal study
Cross-sectional studies suggest that hippocampal volume declines across stages of
psychosis. In contrast, longitudinal studies indicate that hippocampal volume is stable in the …
psychosis. In contrast, longitudinal studies indicate that hippocampal volume is stable in the …
Moving from risk to resilience in psychosis research
Psychosis research has traditionally focused on vulnerability and the detrimental outcomes
of risk exposure. However, there is substantial variability in psychological and functional …
of risk exposure. However, there is substantial variability in psychological and functional …