Behavioural economic theories of addiction contend that greater expected value of drug
relative to alternative non-drug rewards is the core mechanism underpinning vulnerability to …

Rationale Anecdotally, both acute and chronic cannabis use have been associated with
apathy, amotivation, and other reward processing deficits. To date, empirical support for …

Background Cannabis use may be linked with anhedonia and apathy. However, previous
studies have shown mixed results, and few have examined the association between …

Prior findings indicate that trait anhedonia enhances the likelihood of becoming a tobacco
smoker, and preliminary evidence suggests that smoking abstinence leads to anhedonic …

Background The choice for drugs over alternative reinforcers is a translational hallmark
feature of drug addiction. The neural basis of such drug-biased choice is not well …

Rationale Cannabis and tobacco are often smoked simultaneously in joints, and this
practice may increase the risks of developing tobacco and/or cannabis use disorders …

Little is known about the neural functioning that underpins drug valuation and choice in
addiction, including nicotine dependence. Following ad libitum smoking, 19 dependent …

Introduction When animals undergo nicotine deprivation, rewards become less rewarding
(ie, anhedonia occurs). We searched for tests of whether anhedonia occurs in abstinent …

Introduction: Animal studies report abstinence from nicotine makes rewards less rewarding;
however, the results of human tests of the effects of cessation on reward sensitivity are …

Substance use disorders (SUDs) and obesity are both chronic, relapsing, remitting disorders
that arise from a heightened preference for immediate-focused rewards (ie, steep temporal …