The use of whole blood gene expression to derive diagnostic biomarkers capable of
distinguishing between phenotypically similar diseases holds great promise but remains a …

Malaria is a significant cause of global morbidity and mortality. The Plasmodium parasite
has a complex life cycle with mosquito, liver, and blood stages. The blood stages can …

Background Appropriate treatment and management of children presenting with fever
depend on accurate and timely diagnosis, but current diagnostic tests lack sensitivity and …

The complexity of the Plasmodium parasite and its life cycle poses a challenge to our
understanding of the host immune response against malaria. Studying human immune …

CD6 is a cell surface glycoprotein expressed by most T cells and a subset of B cells that has
incompletely-defined roles in regulation of lymphocyte development, selection, activation …

Infections with the deadliest malaria parasite, Plasmodium falciparum, are accompanied by
a strong immunological response of the human host. To date, more than 30 cytokines have …

Neural injuries in cerebral malaria patients are a significant cause of morbidity and mortality.
Nevertheless, a comprehensive research approach to study this issue is lacking, so herein …

The mechanisms behind the ability of Plasmodium falciparum to evade host immune system
are poorly understood and are a major roadblock in achieving malaria elimination. Here, we …

Malaria is a serious, complex disease caused by parasites of the genus Plasmodium.
Plasmodium parasites affect multiple tissues as they evade immune responses, replicate …

Parasites of the phylum Apicomplexa are the causative agents of important diseases such
as malaria, toxoplasmosis or cryptosporidiosis in humans, and babesiosis and coccidiosis in …