Many pollutants cause endocrine disruption in aquatic organisms. While studies of the direct
effects of toxicants on exposed organisms are commonplace, little is known about the …

Early molecular events after the exposure of heavy metals, such as aberrant DNA
methylation, suggest that DNA methylation was important in regulating physiological …

Inbreeding depression is the loss of fitness resulting from the mating of genetically related
individuals. Traditionally, the study of inbreeding depression focused on genetic effects …

A number of chemicals have been shown to affect epigenetic patterning and functions. Since
epigenetic mechanisms regulate transcriptional networks, epigenetic changes induced by …

Epigenome-wide DNA methylation has not been studied in men perinatally exposed to
PCBs and dioxins. Therefore, we examined whether perinatal exposure to polychlorinated …

In vertebrates, estrogens and estrogen mimicking chemicals modulate gene expression
mainly through a genomic pathway mediated by the estrogen receptors (ERs). Although the …

A lab-on-a-chip (LOC) is a microfluidic device (MFD) that integrates several lab functions
into a single chip of only millimeters in size. LOC provides several advantages, such as low …

ABSTRACT A series of studies have assessed the occurrence, levels, and potential adverse
effects of persistent organic pollutants (POP) in fish from Lake Mjøsa. In this lake, high levels …

Epigenetic changes are important mechanisms in the regulation of chromatin structure and
gene expression. Cytosine methylation is one of the major epigenetic modifications …

Genome editing using CRISPR/Cas9 methodology holds much potential to accelerate the
genetic improvement in aquaculture, and has been extensively tested and applied to various …