The role of IL‐1β during human immunodeficiency virus type 1 infection
MM Yaseen, NM Abuharfeil… - Reviews in Medical …, 2023 - Wiley Online Library
Abstract Interleukin (IL)‐1β is a key innate cytokine that is essential for immune activation
and promoting the inflammatory process. However, abnormal elevation in IL‐1β levels has …
and promoting the inflammatory process. However, abnormal elevation in IL‐1β levels has …
Recent advances in myeloid-derived suppressor cell biology
In recent years, studying the role of myeloid-derived suppressor cells (MDSCs) in many
pathological inflammatory conditions has become a very active research area. Although the …
pathological inflammatory conditions has become a very active research area. Although the …
Myeloid-derived suppressor cells and the pathogenesis of human immunodeficiency virus infection
There are several mechanisms by which human immunodeficiency virus (HIV) can mediate
immune dysfunction and exhaustion during the course of infection. Chronic immune …
immune dysfunction and exhaustion during the course of infection. Chronic immune …
The role of p53 in HIV infection
Abstract Purpose of Review This review aims to elucidate the multifaceted role of the tumor
suppressor protein p53 in the context of HIV infection. We explore how p53, a pivotal …
suppressor protein p53 in the context of HIV infection. We explore how p53, a pivotal …
Infusion reactions after receiving the broadly neutralizing antibody VRC01 or placebo to reduce HIV-1 acquisition: results from the phase 2b antibody-mediated …
S Takuva, ST Karuna, M Juraska… - JAIDS Journal of …, 2022 - journals.lww.com
Background: The antibody-mediated prevention (AMP) studies (HVTN 703/HPTN 081 and
HVTN 704/HPTN 085) are harmonized phase 2b trials to assess HIV prevention efficacy and …
HVTN 704/HPTN 085) are harmonized phase 2b trials to assess HIV prevention efficacy and …
Increasing the clinical potential and applications of anti-HIV antibodies
CK Hua, ME Ackerman - Frontiers in immunology, 2017 - frontiersin.org
Preclinical and early human clinical studies of broadly neutralizing antibodies (bNAbs) to
prevent and treat HIV infection support the clinical utility and potential of bNAbs for …
prevent and treat HIV infection support the clinical utility and potential of bNAbs for …
The impact of MDSCs on the efficacy of preventive and therapeutic HIV vaccines
In spite of four decades of research on human immunodeficiency virus (HIV), the virus
remains a major health problem, affecting tens of millions of people around the world. As …
remains a major health problem, affecting tens of millions of people around the world. As …
MDSC expansion during HIV infection: regulators, ART and immune reconstitution
Myeloid-derived suppressor cells (MDSCs) become expanded in different pathological
conditions including human immunodeficiency virus (HIV) infection and this may worsen the …
conditions including human immunodeficiency virus (HIV) infection and this may worsen the …
T-cell evasion and invasion during HIV-1 infection: the role of HIV-1 Tat protein
T-cell-mediated immune responses play indispensable roles in the defense against
infectious pathogens including human immunodeficiency virus type 1 (HIV-1) which can …
infectious pathogens including human immunodeficiency virus type 1 (HIV-1) which can …
Mechanisms and factors that drive extensive human immunodeficiency virus Type-1 Hypervariability: an overview
The extensive hypervariability of human immunodeficiency virus type-1 (HIV-1) populations
represents a major barrier against the success of currently available antiretroviral therapy …
represents a major barrier against the success of currently available antiretroviral therapy …