Cancer transcriptome profiling at the juncture of clinical translation
M Cieślik, AM Chinnaiyan - Nature Reviews Genetics, 2018 - nature.com
Methodological breakthroughs over the past four decades have repeatedly revolutionized
transcriptome profiling. Using RNA sequencing (RNA-seq), it has now become possible to …
transcriptome profiling. Using RNA sequencing (RNA-seq), it has now become possible to …
[HTML][HTML] Regulation of lncRNA and its role in cancer metastasis
J Li, H Meng, Y Bai, K Wang - Oncology research, 2016 - ncbi.nlm.nih.gov
Metastasis is the primary cause of cancer-related death all over the world. Metastasis is a
process by which cancer spreads from the place at which it first arose to distant locations in …
process by which cancer spreads from the place at which it first arose to distant locations in …
Long non-coding RNA MEG3 inhibits NSCLC cells proliferation and induces apoptosis by affecting p53 expression
Abstract Background Long non-coding RNAs play an important role in tumorigenesis,
hence, identification of cancer-associated lncRNAs and investigation of their biological …
hence, identification of cancer-associated lncRNAs and investigation of their biological …
Long noncoding RNAs: Novel insights into hepatocelluar carcinoma
Recent advances in non-protein coding part of human genome analysis have discovered
extensive transcription of large RNA transcripts that lack of coding protein function, termed …
extensive transcription of large RNA transcripts that lack of coding protein function, termed …
Downregulated long noncoding RNA MEG3 is associated with poor prognosis and promotes cell proliferation in gastric cancer
M Sun, R Xia, F Jin, T Xu, Z Liu, W De, X Liu - Tumor Biology, 2014 - Springer
Long noncoding RNAs (lncRNAs) have emerged recently as major players in governing
fundamental biological processes, and many of which are altered in expression and likely to …
fundamental biological processes, and many of which are altered in expression and likely to …
[HTML][HTML] Long non-coding RNAs as novel targets for therapy in hepatocellular carcinoma
MA Parasramka, S Maji, A Matsuda, IK Yan… - Pharmacology & …, 2016 - Elsevier
The recognition of functional roles for transcribed long non-coding RNA (lncRNA) has
provided a new dimension to our understanding of cellular physiology and disease …
provided a new dimension to our understanding of cellular physiology and disease …
EZH2-mediated epigenetic suppression of long noncoding RNA SPRY4-IT1 promote s NSCLC cell proliferation and metastasis by affecting the epithelial …
M Sun, XH Liu, KH Lu, FQ Nie, R Xia, R Kong… - Cell death & …, 2014 - nature.com
Recent evidence indicates that long noncoding RNAs (lncRNAs) have a critical role in the
regulation of cellular processes such as differentiation, proliferation, and metastasis. These …
regulation of cellular processes such as differentiation, proliferation, and metastasis. These …
Transposable elements in human cancer: causes and consequences of deregulation
Transposable elements (TEs) comprise nearly half of the human genome and play an
essential role in the maintenance of genomic stability, chromosomal architecture, and …
essential role in the maintenance of genomic stability, chromosomal architecture, and …
The Long Noncoding RNA MEG3 Contributes to Cisplatin Resistance of Human Lung Adenocarcinoma
Long noncoding RNAs (lncRNAs) have been identified as oncogenes or tumor suppressors
that are involved in tumorigenesis and chemotherapy drug resistance. Maternally expressed …
that are involved in tumorigenesis and chemotherapy drug resistance. Maternally expressed …
A review of current evidence about lncRNA MEG3: A tumor suppressor in multiple cancers
J Xu, X Wang, C Zhu, K Wang - Frontiers in cell and developmental …, 2022 - frontiersin.org
Long non-coding RNA (lncRNA) maternally expressed gene 3 (MEG3) is a lncRNA located
at the DLK1-MEG3 site of human chromosome 14q32. 3. The expression of MEG3 in various …
at the DLK1-MEG3 site of human chromosome 14q32. 3. The expression of MEG3 in various …