Chemical and biological evaluation of thiosemicarbazone-bearing heterocyclic metal complexes
AI Matesanz, JM Herrero… - Current topics in medicinal …, 2021 - ingentaconnect.com
Thiosemicarbazones (TSCNs) constitute a broad family of compounds (R1R2C= N-NH-C (S)-
NR3R4), particularly attractive because many of them display some biological activity …
NR3R4), particularly attractive because many of them display some biological activity …
Benzylpiperidine-linked diarylthiazoles as potential anti-Alzheimer's agents: synthesis and biological evaluation
M Shidore, J Machhi, K Shingala… - Journal of medicinal …, 2016 - ACS Publications
A novel series of hybrid molecules were designed and synthesized by fusing the
pharmacophoric features of cholinesterase inhibitor donepezil and diarylthiazole as …
pharmacophoric features of cholinesterase inhibitor donepezil and diarylthiazole as …
[PDF][PDF] Synthesis of new thiazole and thiazolyl derivatives of medicinal significant-a short review
W Hussein, G Turan - MOJ Biorg. Org. Chem, 2018 - researchgate.net
In the field of therapeutic science, thiazoles are of extraordinary importance, because of their
potent and significant biological activities. Likewise thiazole and their derivatives are found …
potent and significant biological activities. Likewise thiazole and their derivatives are found …
Characterization of prodigiosin pigment by Serratia marcescens and the evaluation of its bioactivities
The aim of the present study is to discover a bacterial pigment providing protection and
prevention of neurological damage and cancer development, which can have a role as a …
prevention of neurological damage and cancer development, which can have a role as a …
Design, synthesis, DFT, molecular docking, and biological evalution of pyrazole derivatives as potent acetyl cholinestrease inhibitors
Alzheimer's disease (AD) is an age-related chronic and progressive neurodegenerative
disease, affecting cognition, memory, and behavior. Treatment of Alzheimer's disease's (AD) …
disease, affecting cognition, memory, and behavior. Treatment of Alzheimer's disease's (AD) …
Synthesis, Antioxidant and Some Enzyme Inhibition Activities of New Sulfonyl Hydrazones and their Molecular Docking Simulations
In this work, a series of new sulfonyl hydrazones were synthesized and screened for
antioxidant and anticholinesterase, tyrosinase and urease enzyme inhibition activities. In …
antioxidant and anticholinesterase, tyrosinase and urease enzyme inhibition activities. In …
Green and four-component cyclocondensation synthesis and in silico docking of new polyfunctionalized pyrrole derivatives as the potential anticholinesterase agents
MH Meshkatalsadat, A Mahmoudi, S Lotfi… - Molecular Diversity, 2022 - Springer
Synthesis of new substituted pyrrole scaffolds containing substituted thiadiazol-2-amine
moiety was successfully developed through one-pot and multi-component tandem …
moiety was successfully developed through one-pot and multi-component tandem …
In vitro anti-Helicobacter pylori, anti-urease and anti-gastric cancer activities of novel hydrazones
In this study, new hydrazone derivatives were synthesized by taking into account the
virulence factor of the urease in the urease-positive microorganism H. pylori. The structure of …
virulence factor of the urease in the urease-positive microorganism H. pylori. The structure of …
New 2-hydrazinothiazole derivatives as potential MAO-A, MAO-B, AChE, and BChE inhibitors
B Tutuş, AE Evren, BN Sağlik Özkan… - Phosphorus, Sulfur, and …, 2024 - Taylor & Francis
The incidence of neurodegenerative Alzheimer's and Parkinson's diseases is increasing
worldwide every day, and treatment options are currently very limited. There is no definitive …
worldwide every day, and treatment options are currently very limited. There is no definitive …
Evaluation of phenolic profile, antioxidant and anticholinesterase effects of Fuscoporia torulosa
In this study, we investigated antioxidant and anticholinesterase activities of the hexane,
chloroform, acetone, methanol and water extracts of F. torulosa mushroom with total …
chloroform, acetone, methanol and water extracts of F. torulosa mushroom with total …