Alginate: current use and future perspectives in pharmaceutical and biomedical applications

M Szekalska, A Puciłowska… - … journal of polymer …, 2016 - Wiley Online Library
Over the last decades, alginates, natural multifunctional polymers, have increasingly drawn
attention as attractive compounds in the biomedical and pharmaceutical fields due to their …

Harnessing knee joint resident mesenchymal stem cells in cartilage tissue engineering

X Xu, L Xu, J Xia, C Wen, Y Liang, Y Zhang - Acta Biomaterialia, 2023 - Elsevier
Osteoarthritis (OA) is a widespread clinical disease characterized by cartilage degeneration
in middle-aged and elderly people. Currently, there is no effective treatment for OA apart …

[HTML][HTML] 3D cell sheet structure augments mesenchymal stem cell cytokine production

S Bou-Ghannam, K Kim, DW Grainger, T Okano - Scientific reports, 2021 - nature.com
Mesenchymal stem cells (MSCs) secrete paracrine factors that play crucial roles during
tissue regeneration. An increasing body of evidence suggests that this paracrine function is …

Mimicking the natural basement membrane for advanced tissue engineering

P Jain, SB Rauer, M Möller, S Singh - Biomacromolecules, 2022 - ACS Publications
Advancements in the field of tissue engineering have led to the elucidation of physical and
chemical characteristics of physiological basement membranes (BM) as specialized forms of …

Strategies to address mesenchymal stem/stromal cell heterogeneity in immunomodulatory profiles to improve cell-based therapies

CM Dunn, S Kameishi, DW Grainger, T Okano - Acta Biomaterialia, 2021 - Elsevier
Mesenchymal stromal cells (MSCs) have gained immense attention over the past two
decades due to their multipotent differentiation potential and pro-regenerative and …

Chorioallantoic membrane assay as model for angiogenesis in tissue engineering: Focus on stem cells

G Merckx, H Tay, M Lo Monaco… - … Engineering Part B …, 2020 - liebertpub.com
Tissue engineering aims to structurally and functionally regenerate damaged tissues, which
requires the formation of new blood vessels that supply oxygen and nutrients by the process …

Regeneration and repair of skin wounds: various strategies for treatment

F Rezaie, M Momeni-Moghaddam… - … journal of lower …, 2019 - journals.sagepub.com
Skin as a mechanical barrier between the inner and outer environment of our body protects
us against infection and electrolyte loss. This organ consists of 3 layers: the epidermis …

Combination product of dermal matrix, human mesenchymal stem cells, and timolol promotes diabetic wound healing in mice

H Yang, F Fierro, M So, DJ Yoon… - Stem cells …, 2020 - academic.oup.com
Diabetic foot ulcers are a major health care concern with limited effective therapies.
Mesenchymal stem cell (MSC)-based therapies are promising treatment options due to their …

[HTML][HTML] Recent strategies for enhancing the therapeutic efficacy of stem cells in wound healing

Y Zhao, M Wang, F Liang, J Li - Stem Cell Research & Therapy, 2021 - Springer
Skin wound healing is a multi-stage process that depends on the coordination of multiple
cells and mediators. Chronic or non-healing wounds resulting from the dysregulation of this …

Multistage extraction and purification of waste Sargassum natans to produce sodium alginate: An optimization approach

A Mohammed, R Bissoon, E Bajnath… - Carbohydrate …, 2018 - Elsevier
Sargassum in the Caribbean region has affected the livelihood of several coastal
communities due to the influx of large quantities of the seaweed in recent times. This article …