G-quadruplexes in cancer-related gene promoters: from identification to therapeutic targeting

F Romano, A Di Porzio, N Iaccarino… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Guanine-rich DNA sequences can fold into four-stranded noncanonical
secondary structures called G-quadruplexes (G4s) which are widely distributed in functional …

CARD11 serves as a therapeutic biomarker for the drug therapies of ccRCC.

K Tian, H CHEN, Q Wang, F Jiang, C Feng, T Li… - …, 2024 - search.ebscohost.com
The incidence of clear cell renal cell carcinoma (ccRCC) is globally high; however, despite
the introduction of innovative drug therapies, there remains a lack of effective biomarkers for …

Caspase recruiting domain-containing protein 11 (CARD11) serves as a therapeutic biomarker for the drug therapies of clear cell renal cell carcinoma

K Tian, Y Tang, Q Wang, C Ye, S Cheng, C Feng, T Li… - 2023 - researchsquare.com
Clear cell renal cell carcinoma (ccRCC) belongs to the ten most diagnosed cancer types
worldwide. Novel drug therapies are introduced and beneficial to the advanced ccRCC but …