Obstructive sleep apnea (OSA), characterized by intermittent hypoxia (IH), is linked with
increased reactive oxygen species/reactive nitrogen species (ROS/RNS) and oxidative …

Intermittent hypoxia (IH) has been the subject of considerable research in recent years, and
triggers a bewildering array of both detrimental and beneficial effects in multiple …

We review progress towards greater mechanistic understanding and clinical translation of a
strategy to improve respiratory and non-respiratory motor function in people with …

Intermittent hypoxia (IH) is most often thought of for its role in morbidity associated with sleep-
disordered breathing, including central nervous system pathology. However, recent …

In recent years, it has become clear that brief, repeated presentations of hypoxia [ie, acute
intermittent hypoxia (AIH)] can boost the efficacy of more traditional therapeutic strategies in …

Intermittent hypoxia has generally been perceived as a high-risk stimulus, particularly in the
field of sleep medicine, because it is thought to initiate detrimental cardiovascular …

Substantial advances have been made recently into the discovery of fundamental
mechanisms underlying the neural control of breathing and even some inroads into …

Acute intermittent hypoxia (AIH) enhances voluntary motor output in humans with central
nervous system damage. The neural mechanisms contributing to these beneficial effects are …

Widespread appreciation that neuroplasticity is an essential feature of the neural system
controlling breathing has emerged only in recent years. In this chapter, we focus on …

Inflammation undermines neuroplasticity, including serotonin-dependent phrenic long-term
facilitation (pLTF) following moderate acute intermittent hypoxia (mAIH: 3, 5-min episodes …