Aggressive pituitary adenomas—diagnosis and emerging treatments

A Di Ieva, F Rotondo, LV Syro, MD Cusimano… - Nature Reviews …, 2014 - nature.com
The WHO categorizes pituitary tumours as typical adenomas, atypical adenomas and
pituitary carcinomas, with typical adenomas constituting the major class. However, the WHO …

Endoscopic endonasal transsphenoidal approach to large and giant pituitary adenomas: institutional experience and predictors of extent of resection

K Juraschka, OH Khan, BL Godoy, E Monsalves… - Journal of …, 2014 - thejns.org
Object While the use of endoscopic approaches has become increasingly accepted in the
resection of pituitary adenomas, limited evidence exists regarding the success of this …

Gross total resection of pituitary adenomas after endoscopic vs. microscopic transsphenoidal surgery: a meta-analysis

RD Almutairi, IS Muskens, DJ Cote, MD Dijkman… - Acta …, 2018 - Springer
Background Microscopic transsphenoidal surgery (mTSS) is a well-established method to
address adenomas of the pituitary gland. Endoscopic transsphenoidal surgery (eTSS) has …

Identification and repair of intraoperative cerebrospinal fluid leaks in endonasal transsphenoidal pituitary surgery: surgical experience in a series of 1002 patients

BA Strickland, J Lucas, B Harris, E Kulubya… - Journal of …, 2017 - thejns.org
OBJECTIVE Cerebrospinal fluid (CSF) rhinorrhea is among the most common complications
following transsphenoidal surgery for sellar region lesions. The aim of this study was to …

Giant pituitary adenomas: surgical outcomes of 50 cases operated on by the endonasal endoscopic approach

JA Gondim, JPC Almeida, LAF Albuquerque… - World neurosurgery, 2014 - Elsevier
Objective To present our experience with the surgical management of giant pituitary
adenomas in a series of 50 cases operated on by an endoscopic endonasal approach …

Visual outcomes after endoscopic endonasal pituitary adenoma resection: a systematic review and meta-analysis

IS Muskens, AH Zamanipoor Najafabadi, V Briceno… - Pituitary, 2017 - Springer
Purpose Patients with pituitary adenomas often present with visual deficits. While the aim of
endoscopic endonasal transsphenoidal surgery (EETS) is to improve these deficits …

Evaluation of outcomes after endoscopic endonasal surgery for large and giant pituitary macroadenoma: a retrospective review of 39 consecutive patients

JD Chabot, S Chakraborty, G Imbarrato… - World neurosurgery, 2015 - Elsevier
Background The endoscopic endonasal approach for pituitary neoplasms has shown similar
efficacy compared with the microscopic approach. However, outcomes and complication …

Transsphenoidal surgery of giant pituitary adenoma: results and experience of 239 cases in a single center

Y Chen, X Xu, J Cao, Y Jie, L Wang, F Cai… - Frontiers in …, 2022 - frontiersin.org
Background Transsphenoidal surgery (TSS) is first-line treatment for giant pituitary
adenomas (PAs). Although PA is a benign neuroendocrine tumor that originates from …

[HTML][HTML] Treatment strategies for giant pituitary adenomas in the era of endoscopic transsphenoidal surgery: a multicenter series

A Micko, MS Agam, A Brunswick, BA Strickland… - Journal of …, 2021 - thejns.org
OBJECTIVE Given the anatomical complexity and frequently invasive growth of giant
pituitary adenomas (GPAs), individually tailored approaches are required. The aim of this …

Endoscopic versus microscopic approach for surgical treatment of acromegaly

H Fathalla, MD Cusimano, A Di Ieva, J Lee… - Neurosurgical …, 2015 - Springer
Transsphenoidal surgery in the setting of acromegaly is quite challenging due to increased
soft tissue mass, bony overgrowth, and bleeding. There is a debate on the endoscopic …