Background Non-typhoidal salmonella can cause serious, life-threatening invasive
infections involving the bloodstream and other normally sterile sites. We aimed to …

Invasive strains of non-typhoidal salmonellae have emerged as a prominent cause of
bloodstream infection in African adults and children, with an associated case fatality of 20 …

This study systematically reviews the literature on the occurrence, incidence and case
fatality rate (CFR) of invasive nontyphoidal Salmonella (iNTS) disease in Africa from 1966 to …

Greater than 80% of malaria-related mortality occurs in sub-Saharan Africa due to infections
with Plasmodium falciparum. The majority of P. falciparum-related mortality occurs in …

Malaria is caused by infection with protozoan parasites of the Plasmodium genus,
transmitted to humans by female anopheline mosquitoes. Plasmodia have adapted to a …

Background. Severe disease attributable to Plasmodium vivax infection is already well
described worldwide; however, autopsies in these patients are scarce. Methods. From 1996 …

Sepsis defined as a dysregulated immune response is a major cause of morbidity in
children. In sub-Saharan Africa, the clinical features of sepsis overlap with other frequent …

Background Severe malaria remains a major cause of pediatric hospital admission across
Africa. Invasive bacterial infection (IBI) is a recognized complication of Plasmodium …

Objectives To assess the performance of WHO's “Guidelines for care at the first-referral level
in developing countries” in an area of intense malaria transmission and identify bacterial …

The resurgence of the malaria eradication agenda and the increasing number of severe
manifestation reports has contributed to a renewed interested in the Plasmodium vivax …