[HTML][HTML] The human virome: assembly, composition and host interactions

G Liang, FD Bushman - Nature Reviews Microbiology, 2021 - nature.com
The human body hosts vast microbial communities, termed the microbiome. Less well
known is the fact that the human body also hosts vast numbers of different viruses …

[HTML][HTML] Bacteriophages of the human gut: the “known unknown” of the microbiome

AN Shkoporov, C Hill - Cell host & microbe, 2019 - cell.com
The human gut microbiome is a dense and taxonomically diverse consortium of
microorganisms. While the bacterial components of the microbiome have received …

[HTML][HTML] Metagenomic compendium of 189,680 DNA viruses from the human gut microbiome

S Nayfach, D Páez-Espino, L Call, SJ Low… - Nature …, 2021 - nature.com
Bacteriophages have important roles in the ecology of the human gut microbiome but are
under-represented in reference databases. To address this problem, we assembled the …

[HTML][HTML] Expanding known viral diversity in the healthy infant gut

SA Shah, L Deng, J Thorsen, AG Pedersen… - Nature …, 2023 - nature.com
The gut microbiome is shaped through infancy and impacts the maturation of the immune
system, thus protecting against chronic disease later in life. Phages, or viruses that infect …

[HTML][HTML] The human gut virome is highly diverse, stable, and individual specific

AN Shkoporov, AG Clooney, TDS Sutton, FJ Ryan… - Cell host & …, 2019 - cell.com
The human gut contains a vast array of viruses, mostly bacteriophages. The majority remain
uncharacterized, and their roles in shaping the gut microbiome and in impacting on human …

[HTML][HTML] The gut virome database reveals age-dependent patterns of virome diversity in the human gut

AC Gregory, O Zablocki, AA Zayed, A Howell… - Cell host & …, 2020 - cell.com
The gut microbiome profoundly affects human health and disease, and their infecting viruses
are likely as important, but often missed because of reference database limitations. Here, we …

[HTML][HTML] A review on the applications of next generation sequencing technologies as applied to food-related microbiome studies

Y Cao, S Fanning, S Proos, K Jordan… - Frontiers in …, 2017 - frontiersin.org
The development of next generation sequencing (NGS) techniques has enabled
researchers to study and understand the world of microorganisms from broader and deeper …

[HTML][HTML] Gut bacteriophage: current understanding and challenges

TDS Sutton, C Hill - Frontiers in endocrinology, 2019 - frontiersin.org
The gut microbiome is widely accepted to have a significant impact on human health yet,
despite years of research on this complex ecosystem, the contributions of different forces …

Bacteriophages and their potential for treatment of gastrointestinal diseases

Y Duan, R Young, B Schnabl - Nature reviews Gastroenterology & …, 2022 - nature.com
Although bacteriophages have been overshadowed as therapeutic agents by antibiotics for
decades, the emergence of multidrug-resistant bacteria and a better understanding of the …

[HTML][HTML] Modular approach to customise sample preparation procedures for viral metagenomics: a reproducible protocol for virome analysis

N Conceição-Neto, M Zeller, H Lefrère, P De Bruyn… - Scientific reports, 2015 - nature.com
A major limitation for better understanding the role of the human gut virome in health and
disease is the lack of validated methods that allow high throughput virome analysis. To …