Malignant brain tumors rank among the most challenging type of malignancies to manage.
The current treatment protocol commonly entails surgery followed by radiotherapy and/or …

Background Although immunotherapy has been widely used, there is currently no research
comparing immunotherapy for non-small cell lung cancer (NSCLC) patients with brain …

Importance In 2015, first-line programmed cell death 1 (PD-1) immune checkpoint inhibitors
(ICI) were Food and Drug Administration (FDA)-approved and National Comprehensive …

Brain metastasis (BrM) is a devastating complication of solid tumors associated with poor
outcomes. Immune-checkpoint inhibitors (ICI) have revolutionized the treatment of cancer …

Importance Systemic steroids are commonly used to manage immune-related adverse
events (irAEs), but it remains unclear whether they may undermine immune checkpoint …

Introduction Cancer is a major global health concern, and immune checkpoint inhibitors
(ICIs) offer a promising treatment option for cancer patients. However, the efficacy of ICIs can …

The traditional picture of cancer patients as weak individuals requiring maximum rest and
protection is beginning to dissolve. Too much focus on the medical side and one's own …

Background Melanoma is the most serious type of skin cancer, and surgery is an effective
method to treat melanoma. Unfortunately, local residual micro-infiltrated tumour cells and …

Simple Summary Since the approval of immune checkpoint inhibitors for solid tumors,
concerns have been raised about the role of the microbiota on immunotherapy success and …

Despite significant advances in our knowledge regarding the genetics and molecular
biology of gliomas over the past two decades and hundreds of clinical trials, no effective …