Preventing microbial infections with natural phenolic compounds

K Ecevit, AA Barros, JM Silva, RL Reis - Future Pharmacology, 2022 - mdpi.com
The struggle between humans and pathogens has taken and is continuing to take countless
lives every year. As the misusage of conventional antibiotics increases, the complexity …

Coumarin‐containing hybrids and their antibacterial activities

D Feng, A Zhang, Y Yang, P Yang - Archiv der Pharmazie, 2020 - Wiley Online Library
Infections caused by Gram‐positive and‐negative bacteria are one of the foremost causes of
morbidity and mortality globally. Antibiotics are the mainstay of therapy for bacterial …

New organoruthenium (II) complexes containing N, X-donor (X= O, S) heterocyclic chelators: synthesis, spectral characterization, in vitro cytotoxicity and apoptosis …

G Kalaiarasi, MM Subarkhan, CKF Safwana… - Inorganica chimica …, 2022 - Elsevier
Four Schiff base ligands namely ((1E)-1-(1-(6-chloro-2-oxo-2H-chromen-3-yl) ethylidene)
semicarbazide)(HL 1),((1E)-1-(1-(6-chloro-2-oxo-2H-chromen-3-yl) ethylidene …

Molecular insights into coumarin analogues as antimicrobial agents: Recent developments in drug discovery

RS Cheke, HM Patel, VM Patil, IA Ansari, JP Ambhore… - Antibiotics, 2022 - mdpi.com
Simple Summary Coumarins are a large family of benzopyrones, and more than 1300
coumarins have been reported to date. Natural, as well as synthetic, coumarins have …

Molecular docking studies of coumarin hybrids as potential acetylcholinesterase, butyrylcholinesterase, monoamine oxidase A/B and β-amyloid inhibitors for …

SK Yusufzai, MS Khan, O Sulaiman, H Osman… - Chemistry Central …, 2018 - Springer
Coumarins are the phytochemicals, which belong to the family of benzopyrone, that display
interesting pharmacological properties. Several natural, synthetic and semisynthetic …

A novel coumarin based probe for Al (III): synthesis, spectral characterization, photophysical properties, DFT calculations and fluorescence cellular bio-imaging

G Kalaiarasi, M Ranjani, R Prabhakaran… - Inorganica Chimica …, 2022 - Elsevier
A new coumarin based sensor probe,(E)-7-hydroxy-3 (2-(2-(1-(2-oxo-2H-chromen-3-yl)
ethylidene) hydrazinyl) oxazol-4-yl)-2H-chromen-2-one (7HACOX) was designed …

Synthesis and potential antimicrobial activity of novel α-aminophosphonates derivatives bearing substituted quinoline or quinolone and thiazole moieties

B Litim, A Djahoudi, S Meliani, A Boukhari - Medicinal Chemistry …, 2022 - Springer
To develop novel antimicrobial agents, and based on the biologically active heterocyclic
quinoline and thiazole substituted, a series of novel α-aminophosphonates (9a–h) and (10i …

[HTML][HTML] Medicinal significance of novel coumarin analogs: Recent studies

SB Patil - Results in Chemistry, 2022 - Elsevier
Coumarin is a versatile scaffold with outstanding biological potential and played a key role
in the field of medicine. The benzopyran-2-one ring bearing heterocycles are known for …

Multicomponent synthesis of chromophores–The one-pot approach to functional π-systems

L Brandner, TJJ Müller - Frontiers in Chemistry, 2023 - frontiersin.org
Multicomponent reactions, conducted in a domino, sequential or consecutive fashion, have
not only considerably enhanced synthetic efficiency as one-pot methodology, but they have …

3-(Bromoacetyl) coumarins: unraveling their synthesis, chemistry, and applications

MM Abdou, A Abu-Rayyan, AG Bedir, S Abdel-Fattah… - RSC …, 2021 - pubs.rsc.org
This review emphasizes recent developments in synthetic routes of 3-(bromoacetyl)
coumarin derivatives. Also, chemical reactions of 3-(bromoacetyl) coumarins as versatile …