The two leading causes of failure for joint arthroplasty prostheses are aseptic loosening and
periprosthetic joint infection. With the number of primary and revision joint replacement …

Pyroptosis is a form of necrotic and inflammatory programmed cell death, which could be
characterized by cell swelling, pore formation on plasma membranes, and release of …

Antimicrobial peptides and proteins (AMPs) are a diverse class of naturally occurring
molecules that are produced as a first line of defense by all multicellular organisms. These …

Diabetes and obesity are two metabolic diseases characterized by insulin resistance and a
low-grade inflammation. Seeking an inflammatory factor causative of the onset of insulin …

Abstract Interferon-γ (IFN-γ) coordinates a diverse array of cellular programs through
transcriptional regulation of immunologically relevant genes. This article reviews the current …

Consumption of diets high in fat and calories leads to hyperphagia and obesity, which is
associated with chronic “low-grade” systemic inflammation. Ingestion of a high-fat diet alters …

Lipopolysaccharide (LPS [endotoxin]) is the principal component of the outer membrane of
Gram-negative bacteria. Recent studies have elucidated how LPS is recognized by …

TLR4 is a member of the recently identified Toll-like receptor family of proteins and has been
putatively identified as Lps, the gene necessary for potent responses to lipopolysaccharide …

Bacterial lipopolysaccharides (LPS) are the major outer surface membrane components
present in almost all Gram-negative bacteria and act as extremely strong stimulators of …

The use of fluorescent probes in visible detection has been developed over the last several
decades. Biomolecules are essential in the biological processes of organisms, and their …