Beyond deep reinforcement learning: A tutorial on generative diffusion models in network optimization

H Du, R Zhang, Y Liu, J Wang, Y Lin, Z Li… - arXiv preprint arXiv …, 2023 - arxiv.org
Generative Diffusion Models (GDMs) have emerged as a transformative force in the realm of
Generative Artificial Intelligence (GAI), demonstrating their versatility and efficacy across a …

Opportunities and challenges for machine learning-assisted enzyme engineering

J Yang, FZ Li, FH Arnold - ACS Central Science, 2024 - ACS Publications
Enzymes can be engineered at the level of their amino acid sequences to optimize key
properties such as expression, stability, substrate range, and catalytic efficiency─ or even to …

Generalized biomolecular modeling and design with RoseTTAFold All-Atom

R Krishna, J Wang, W Ahern, P Sturmfels, P Venkatesh… - Science, 2024 - science.org
Deep-learning methods have revolutionized protein structure prediction and design but are
presently limited to protein-only systems. We describe RoseTTAFold All-Atom (RFAA), which …

MeLM, a generative pretrained language modeling framework that solves forward and inverse mechanics problems

MJ Buehler - Journal of the Mechanics and Physics of Solids, 2023 - Elsevier
We report a flexible multi-modal mechanics language model, MeLM, applied to solve
various nonlinear forward and inverse problems, that can deal with a set of instructions …

Proteininvbench: Benchmarking protein inverse folding on diverse tasks, models, and metrics

Z Gao, C Tan, Y Zhang, X Chen… - Advances in Neural …, 2024 - proceedings.neurips.cc
Protein inverse folding has attracted increasing attention in recent years. However, we
observe that current methods are usually limited to the CATH dataset and the recovery …

Unleashing the power of artificial intelligence in materials design

S Badini, S Regondi, R Pugliese - Materials, 2023 - mdpi.com
The integration of artificial intelligence (AI) algorithms in materials design is revolutionizing
the field of materials engineering thanks to their power to predict material properties, design …

ForceGen: End-to-end de novo protein generation based on nonlinear mechanical unfolding responses using a language diffusion model

B Ni, DL Kaplan, MJ Buehler - Science Advances, 2024 - science.org
Through evolution, nature has presented a set of remarkable protein materials, including
elastins, silks, keratins and collagens with superior mechanical performances that play …

BioinspiredLLM: Conversational Large Language Model for the Mechanics of Biological and Bio‐Inspired Materials

RK Luu, MJ Buehler - Advanced Science, 2024 - Wiley Online Library
The study of biological materials and bio‐inspired materials science is well established;
however, surprisingly little knowledge is systematically translated to engineering solutions …

Navigating generative artificial intelligence promises and perils for knowledge and creative work

H Benbya, F Strich, T Tamm - Journal of the Association for …, 2024 - aisel.aisnet.org
Generative artificial intelligence (GenAI) is rapidly becoming a viable tool to enhance
productivity and act as a catalyst for innovation across various sectors. Its ability to perform …

Untapped potential of deep eutectic solvents for the synthesis of bioinspired inorganic–organic materials

M Wysokowski, RK Luu, S Arevalo, E Khare… - Chemistry of …, 2023 - ACS Publications
Since the discovery of deep eutectic solvents (DESs) in 2003, significant progress has been
made in the field, specifically advancing aspects of their preparation and physicochemical …