Nano-drug co-delivery system of natural active ingredients and chemotherapy drugs for cancer treatment: a review

B Li, H Shao, L Gao, H Li, H Sheng, L Zhu - Drug Delivery, 2022 - Taylor & Francis
Chemotherapy drugs have been used for a long time in the treatment of cancer, but serious
side effects are caused by the inability of the drug to be solely delivered to the tumor when …

[HTML][HTML] Teaching the basics of the mechanism of doxorubicin-induced cardiotoxicity: Have we been barking up the wrong tree?

B Kalyanaraman - Redox biology, 2020 - Elsevier
Abstract Doxorubicin (DOX), or Adriamycin, an anthracycline antibiotic discovered
serendipitously as a chemotherapeutic drug several decades ago, is still one of the most …

Honokiol: A review of its pharmacological potential and therapeutic insights

A Rauf, A Olatunde, M Imran, FA Alhumaydhi… - Phytomedicine, 2021 - Elsevier
Background Honokiol is a pleiotropic compound which been isolated from Magnolia species
such as Magnolia grandiflora and Magnolia dealbata. Magnolia species Magnolia …

[HTML][HTML] Research progress of therapeutic drugs for doxorubicin-induced cardiomyopathy

Y Chen, S Shi, Y Dai - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Doxorubicin (DOX), as a kind of chemotherapy agent with remarkable therapeutic effect, can
be used to treat diverse malignant tumors clinically. Dose-dependent cardiotoxicity is the …

[HTML][HTML] Role of acetylation in doxorubicin-induced cardiotoxicity

D Li, Y Yang, S Wang, X He, M Liu, B Bai, C Tian… - Redox Biology, 2021 - Elsevier
As a potent chemotherapeutic agent, doxorubicin (DOX) is widely used for the treatment of a
variety of cancers However, its clinical utility is limited by dose-dependent cardiotoxicity, and …

Therapeutic potential of polyphenols in cardiovascular diseases: Regulation of mTOR signaling pathway

A Sanches-Silva, L Testai, SF Nabavi, M Battino… - Pharmacological …, 2020 - Elsevier
Cardiovascular diseases comprise of non-communicable disorders that involve the heart
and/or blood vessels and have become the leading cause of death worldwide with …

Honokiol: a review of its anticancer potential and mechanisms

CP Ong, WL Lee, YQ Tang, WH Yap - Cancers, 2019 - mdpi.com
Cancer is characterised by uncontrolled cell division and abnormal cell growth, which is
largely caused by a variety of gene mutations. There are continuous efforts being made to …

Effects of doxorubicin‐induced cardiotoxicity on cardiac mitochondrial dynamics and mitochondrial function: Insights for future interventions

N Osataphan, A Phrommintikul… - Journal of Cellular …, 2020 - Wiley Online Library
Anthracyclines is an effective chemotherapeutic treatment used for many types of cancer.
However, high cumulative dosage of anthracyclines leads to cardiac toxicity and heart …

Nerolidol attenuates oxidative stress, inflammation, and apoptosis by modulating Nrf2/MAPK signaling pathways in doxorubicin-induced acute cardiotoxicity in rats

S Arunachalam, MF Nagoor Meeran, S Azimullah… - Antioxidants, 2021 - mdpi.com
The clinical usage of doxorubicin (DOX), a potent anthracycline antineoplastic drug, is often
limited by its cardiotoxic effects. Thus, for improving usage of DOX, the aim of this study was …

Inflammation suppression in doxorubicin-induced cardiotoxicity: natural compounds as therapeutic options

F Yarmohammadi, H Karbasforooshan… - Naunyn-Schmiedeberg's …, 2021 - Springer
Doxorubicin (DOX) is a potent chemotherapeutic agent; however, the accompanying
cardiotoxicity is a significant complication of the usefulness of treatment with DOX. Multiple …