Alzheimer's disease (AD) is pathologically defined by the presence of fibrillar amyloid β (Aβ)
peptide in extracellular senile plaques and tau filaments in intracellular neurofibrillary …

The blood coagulation protein fibrinogen is deposited in the brain in a wide range of
neurological diseases and traumatic injuries with blood–brain barrier (BBB) disruption …

INTRODUCTION The choroid plexus is a secretory epithelial tissue of the central nervous
system (CNS) responsible for cerebrospinal fluid (CSF) production and functions as a barrier …

Astrocyte reactivity is a hallmark of neuroinflammation that arises with Alzheimer's disease
(AD) and nearly every other neurodegenerative condition. While astrocytes certainly …

Alzheimer's disease (AD) is the most common form of dementia and has no effective
treatment. Besides the well-known pathologic characteristics, this disease also has a …

Alzheimer's disease (AD) is characterized by amyloid-β (Aβ) plaques, tau tangles, brain
atrophy, and vascular pathology. Vascular defects include cerebrovascular dysfunction …

Abstract Alzheimer's disease (AD), the most common form of dementia, is characterized by
progressive neurodegeneration leading to severe cognitive decline and eventual death. AD …

Introduction Breast cancer is a complex heterogeneous disease and is a leading cause of
death in women. Early diagnosis and monitoring progression of breast cancer are important …

The fundamental pathology in Alzheimer's disease (AD) is neuronal dysfunction leading to
cognitive impairment. The amyloid-β peptide (Aβ), derived from amyloid precursor protein, is …

Background During the last two decades, over 100 proteomics studies have identified a
variety of potential biomarkers in CSF of Alzheimer's (AD) patients. Although several reviews …