Due to complicated anatomical and physical properties, targeted drug delivery to ocular
tissues continues to be a key challenge for formulation scientists. Various attempts are …

The field of Cannabis sativa L. research for medical purposes has been rapidly advancing in
recent decades and a growing body of evidence suggests that phytocannabinoids are …

Mucus is a complex viscoelastic gel and acts as a barrier covering much of the soft tissue in
the human body. High vascularization and accessibility have motivated drug delivery to …

Sufficient ocular bioavailability is often considered a challenge by the researchers, due to
the complex structure of the eye and its protective physiological mechanisms. In addition, the …

Therapeutic proteins are well-tolerated bioactive compounds used in different therapies, due
to its high specificity and biopotency. Nevertheless, they may also present some …

Lipid nanoparticles (LNPs), composed of ionized lipids, helper lipids, and cholesterol,
provide general therapeutic effects by facilitating intracellular transport and avoiding …

Nanotherapeutics based on biocompatible lipid matrices allow for enhanced solubility of
poorly soluble compounds in the treatment of ophthalmic diseases, overcoming the …

Introduction Retinal diseases are one of the main reasons for vision loss where all available
drug treatments are based on invasive drug administration such as intravitreal injections …

Ocular infection induced by bacteria and fungi is a major cause of visual impairment and
blindness. Topical administration of antibiotics remains the first-line treatment, as effective …

Abstract According to the World Health Organization (WHO) and Centers for Disease Control
and Prevention (CDC), bacterial infections are one of the greatest threats to global health …