Strategies for management of patients with, or at risk for, medication-related osteonecrosis of
the jaw (MRONJ) were set forth in the American Association of Oral and Maxillofacial …

Abstract Purpose of Review Osteonecrosis of the jaw (ONJ) is a rare and severe necrotic
bone disease reflecting a compromise in the body's osseous healing mechanisms and …

Osteonecrosis of the jaw (ONJ) was defined as exposed, necrotic bone in the maxillofacial
region for at least 8 weeks in patients receiving an antiresorptive medication for primary or …

Osteoclasts are cells of haematopoietic origin that are uniquely specialized to degrade
bone. Under physiological conditions, the osteoclastogenesis pathway depends on …

Osteonecrosis of the jaw (ONJ) is a well‐recognized complication of antiresorptive
medications, such as bisphosphonates (BPs). Although ONJ is most common after tooth …

Background A giant cell tumor of bone is a primary benign but locally aggressive neoplasm.
Malignant transformation in a histologically typical giant cell tumor of bone, without …

Even though inflammatory conditions are known to exert adverse effects on bone
metabolism, there are no published data regarding SARS-CoV-2 infection and subsequent …

Osteoprotegerin (OPG) is a 401 amino acid N-glycosylated protein, which is highly
expressed in a large number of tissues. OPG mainly binds to two ligands, ie RANKL …

Transcription factors play important roles in the regulation of cartilage development by
controlling the expression of chondrogenic genes. Genetic studies have revealed that …

Osteoporosis is a metabolic bone disorder affecting million of people worldwide. Increased
understanding of bone disease has led to a greater recognition of factors affecting bones …