With the increasing promise of long-term survival with immune checkpoint blockade (ICB)
therapies, particularly for patients with advanced melanoma, clinicians and investigators are …

Neutrophils have emerged as important players in the tumor microenvironment, largely
attributed to their plasticity and heterogeneity. Evidence accumulated thus far indicates that …

Background Elevated pre-treatment neutrophil-to-lymphocyte ratio (NLR) may reflect
immune dysfunction and is negatively prognostic in cancer patients treated with …

Objectives Immune checkpoint inhibitors (ICIs) are one of the most significant oncological
treatment modalities as a result of the rapid advancement of immunotherapy. Programmed …

Determining the prognostic association of different immune cell types in the tumor
microenvironment is critical for understanding cancer biology and developing new …

We evaluated the prognostic value of hypoalbuminemia in context of various biomarkers at
baseline, including clinical, genomic, transcriptomic, and blood-based markers, in patients …

Anti‐programmed cell death protein‐1 (PD‐1) antibodies have become a standard treatment
for advanced melanoma. However, a predictive biomarker for assessing the efficacy of anti …

Methods A total of 216 lung cancer patients from Tianjin Medical University Cancer Institute
& Hospital who received immunotherapy between 2017 and 2021 were included in the …

In the field of advanced melanoma, there is an urgent need to investigate novel approaches
targeting specific components of the cancer–immunity cycle beyond immune checkpoint …

The neutrophil to lymphocyte ratio (NLR), calculated as the absolute neutrophil count
divided by the absolute lymphocyte count in the peripheral blood, is believed to help risk …