Cytokinin nucleosides-natural compounds with a unique spectrum of biological activities
M S. Drenichev, V E. Oslovsky… - Current topics in …, 2016 - benthamdirect.com
Cytokinin nucleosides exhibit antitumor, antiviral, antiprotozoal, blood pressure reducing,
anti-inflammatory, and antipsychotic activity. These compounds also influence platelet …
anti-inflammatory, and antipsychotic activity. These compounds also influence platelet …
Bioorthogonal labeling and profiling of N6-isopentenyladenosine (i6A) modified RNA
Y Li, H Zhou, S Chen, Y Li, Y Guo, X Chen… - Nucleic Acids …, 2024 - academic.oup.com
Chemical modifications in RNAs play crucial roles in diversifying their structures and
regulating numerous biochemical processes. Since the 1990s, several hydrophobic prenyl …
regulating numerous biochemical processes. Since the 1990s, several hydrophobic prenyl …
Dinucleoside polyphosphates act as 5′-RNA caps in bacteria
O Hudeček, R Benoni, PE Reyes-Gutierrez… - Nature …, 2020 - nature.com
It has been more than 50 years since the discovery of dinucleoside polyphosphates (Np n
Ns) and yet their roles and mechanisms of action remain unclear. Here, we show that both …
Ns) and yet their roles and mechanisms of action remain unclear. Here, we show that both …
Adenosine: Synthetic methods of its derivatives and antitumor activity
FZ Valdés, VZ Luna, BR Arévalo… - Mini Reviews in …, 2018 - ingentaconnect.com
Since 1929, several researchers have conducted studies in relation to the nucleoside of
adenosine (1) mainly distribution identifying, characterizing their biological importance and …
adenosine (1) mainly distribution identifying, characterizing their biological importance and …
From synthesis to the biological effect of isoprenoid 2′-deoxyriboside and 2′, 3′-dideoxyriboside cytokinin analogues
V Matušková, M Zatloukal, T Pospíšil, J Voller… - Phytochemistry, 2023 - Elsevier
Isoprenoid cytokinins are a class of naturally occurring plant signaling molecules. A series of
prepared compounds derived from isoprenoid cytokinins (isopentenyladenine, trans-zeatin …
prepared compounds derived from isoprenoid cytokinins (isopentenyladenine, trans-zeatin …
Cytotoxicity reduction by O-nicotinoylation of antiviral 6-benzylaminopurine ribonucleosides
AA Zenchenko, VE Oslovsky, IV Varizhuk, EV Karpova… - Toxicology in Vitro, 2022 - Elsevier
One of the promising approaches in the development of nucleoside prodrugs is to use the
nucleoside analogs containing lipophilic biodegradable residues, which are cleaved to …
nucleoside analogs containing lipophilic biodegradable residues, which are cleaved to …
Synthesis of triazole-linked SAM-Adenosine conjugates: functionalization of adenosine at N-1 or N-6 position without protecting groups
C Atdjian, D Coelho, L Iannazzo, M Ethève-Quelquejeu… - Molecules, 2020 - mdpi.com
More than 150 RNA chemical modifications have been identified to date. Among them,
methylation of adenosine at the N-6 position (m6A) is crucial for RNA metabolism, stability …
methylation of adenosine at the N-6 position (m6A) is crucial for RNA metabolism, stability …
In Vitro and In Vivo Evidence for RNA Adduction Resulting from Metabolic Activation of Methyleugenol
X Yang, Y Feng, Z Zhang, H Wang, W Li… - Journal of Agricultural …, 2020 - ACS Publications
Methyleugenol (ME) is a ubiquitous component in spices and other culinary herbal products.
A prevailing theory in ME toxicity is its ability to be metabolically activated by P450 enzymes …
A prevailing theory in ME toxicity is its ability to be metabolically activated by P450 enzymes …
Inositol Adenophostin: Convergent Synthesis of a Potent Agonist of d-myo-Inositol 1,4,5-Trisphosphate Receptors
d-myo-Inositol 1, 4, 5-trisphosphate receptors (IP3Rs) are Ca2+ channels activated by the
intracellular messenger inositol 1, 4, 5-trisphosphate (IP3, 1). The glyconucleotide …
intracellular messenger inositol 1, 4, 5-trisphosphate (IP3, 1). The glyconucleotide …
Comparative study of inorganic, boron-rich cluster and organic, phenyl adenosine modifications: synthesis and properties
A Mieczkowski, A Kierozalska… - Future Medicinal …, 2019 - Taylor & Francis
Background: Nucleoside analogs are important class of chemotherapeutics. One of the
original openings in the nucleoside medicinal chemistry was derivatives comprising a boron …
original openings in the nucleoside medicinal chemistry was derivatives comprising a boron …