microRNAs (miRNAs) are small non‐coding RNAs that regulate gene expression post‐
transcriptionally by interfering with the translation of one or more target mRNAs. The unique …

During the last decade, it has become clear that aberrant microRNA expression has a
functional role in the initiation and progression of colorectal cancer (CRC). Specific …

Rationale: microRNAs (miRNAs) modulate gene expression by repressing translation of
targeted genes. Previous work has established a role for miRNAs in regulating vascular …

Autophagy is an evolutionarily conserved mechanism of cellular self‐digestion in which
proteins and organelles are degraded through delivery to lysosomes. Defects in this process …

In the early years of the molecular biology revolution, cancer research was mainly focused
on genetic changes (ie, those that altered DNA sequences). Although this has been …

Inflammatory signaling underlies many diseases, from arthritis to cancer. Our understanding
of inflammation has thus far been limited to the world of proteins, because we are only just …

MiR-145 can regulate cell apoptosis, proliferation, neural development and stem cell
differentiation. Previous studies indicate that miR-145 is downregulated in human colon …

BACKGROUND Repeated implantation failure (RIF) is a major problem encountered in IVF.
We have previously reported that RIF-IVF patients have a different endometrial gene …

Small noncoding RNAs, as post-translational regulators of many target genes, are not only
markers of neoplastic disease initiation and progression, but also markers of response to …

Background Gastric cancer is the fourth most common cancer in the world and the second
most prevalent cause of cancer related death. The development of gastric cancer is mainly …