Production of recombinant proteins generates a variety of process-related impurities. The
multistep manufacturing processes may introduce many potential contaminants into the final …

Thephase problem'in crystallography results from the inability to directly measure the
phases of individual diffracted X-ray waves. While intensities are directly measured during …

Despite the growing interest in membrane proteins, their crystallization remains a major
challenge. In the course of a crystallographic study on the multidrug ATP-binding cassette …

Affinity purification of Strep-tagged fusion proteins on resins carrying an engineered
streptavidin (Strep-Tactin) has become a widely used method for isolation of protein …

Attempts to crystallize several mammalian proteins overexpressed in Escherichia coli
revealed a common contaminant, triosephosphate isomerase, a protein involved in glucose …

Cell surface receptors allowthe cell to sense and respond to external signals. Receptor
malfunctions are associated with many diseases. The diffusional behavior of receptors is of …