Properties, potentials, and prospects of antifreeze proteins
S Venketesh, C Dayananda - Critical reviews in biotechnology, 2008 - Taylor & Francis
Antifreeze proteins (AFPs) are a group of proteins that protect organisms from deep freezing
temperatures and are expressed in vertebrates, invertebrates, plants, bacteria, and fungi …
temperatures and are expressed in vertebrates, invertebrates, plants, bacteria, and fungi …
Use of folding modulators to improve heterologous protein production in Escherichia coli
O Kolaj, S Spada, S Robin, JG Wall - Microbial cell factories, 2009 - Springer
Despite the fundamental importance of E. coli in the manufacture of a wide range of
biotechnological and biomedical products, extensive process and/or target optimisation is …
biotechnological and biomedical products, extensive process and/or target optimisation is …
The molecular basis for modulation of human Vγ9Vδ2 T cell responses by CD277/butyrophilin-3 (BTN3A)-specific antibodies
A Palakodeti, A Sandstrom, L Sundaresan… - Journal of Biological …, 2012 - ASBMB
Human Vγ9Vδ2 T cells are well known for their rapid and potent response to infection and
tumorigenesis when in the presence of endogenous or exogenous phosphoisoprenoids …
tumorigenesis when in the presence of endogenous or exogenous phosphoisoprenoids …
Structural evidence for a germline-encoded T cell receptor–major histocompatibility complex interaction'codon'
All complexes of T cell receptors (TCRs) bound to peptide–major histocompatibility complex
(pMHC) molecules assume a stereotyped binding'polarity', despite wide variations in TCR …
(pMHC) molecules assume a stereotyped binding'polarity', despite wide variations in TCR …
[HTML][HTML] Identification of natural regulatory T cell epitopes reveals convergence on a dominant autoantigen
Regulatory T (Treg) cells expressing the transcription factor Foxp3 are critical for the
prevention of autoimmunity and the suppression of anti-tumor immunity. The major self …
prevention of autoimmunity and the suppression of anti-tumor immunity. The major self …
Surface plasmon resonance for high‐throughput ligand screening of membrane‐bound proteins
JA Maynard, NC Lindquist… - Biotechnology …, 2009 - Wiley Online Library
Technologies based on surface plasmon resonance (SPR) have allowed rapid, label‐free
characterization of protein‐protein and protein‐small molecule interactions. SPR has …
characterization of protein‐protein and protein‐small molecule interactions. SPR has …
An autonomous CDR3δ is sufficient for recognition of the nonclassical MHC class I molecules T10 and T22 by γδ T cells
It remains unclear whether γδ T cell antigen receptors (TCRs) detect antigens in a way
similar to antibodies or αβ TCRs. Here we show that reactivity between the G8 and KN6 γδ …
similar to antibodies or αβ TCRs. Here we show that reactivity between the G8 and KN6 γδ …
Application of phage display for T-cell receptor discovery
The immune system is tasked to keep our body unharmed and healthy. In the immune
system, B-and T-lymphocytes are the two main components working together to stop and …
system, B-and T-lymphocytes are the two main components working together to stop and …
Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain VαVβ fragments
SA Richman, DH Aggen, ML Dossett… - Molecular …, 2009 - Elsevier
The variable (V) domains of antibodies and T cell receptors (TCRs) share sequence
homology and striking structural similarity. Single-chain antibody V domain constructs (scFv) …
homology and striking structural similarity. Single-chain antibody V domain constructs (scFv) …
Display, engineering, and applications of antigen-specific T cell receptors
SA Richman, DM Kranz - Biomolecular engineering, 2007 - Elsevier
The use of T cell receptors (TCRs) as potential therapeutic agents provides an opportunity to
target a greatly expanded array of antigens, compared to those now targeted with …
target a greatly expanded array of antigens, compared to those now targeted with …