International consensus on the prevention of venous and arterial thrombotic events in patients with inflammatory bowel disease

PA Olivera, S Zuily, PG Kotze, V Regnault… - Nature Reviews …, 2021 - nature.com
Patients with inflammatory bowel disease (IBD) are at increased risk of thrombotic events.
Therapies for IBD have the potential to modulate this risk. The aims of this Evidence-Based …

Balancing benefit vs risk of immunosuppressive therapy for individual patients with inflammatory bowel diseases

L Beaugerie, J Kirchgesner - Clinical Gastroenterology and Hepatology, 2019 - Elsevier
Inflammatory bowel diseases (IBD) and their treatments, particularly immunosuppressive
drugs, increase risk of infections and cancers. However, by promoting mucosal healing …

Harms with placebo in trials of biological therapies and small molecules as maintenance therapy in inflammatory bowel disease: a systematic review and meta …

B Gros, J Blackwell, J Segal, CJ Black… - The Lancet …, 2024 - thelancet.com
Background Randomised placebo-controlled trials for the induction of inflammatory bowel
disease (IBD) remission involve potential harms to those receiving placebo. Whether these …

Harms with placebo in trials of biological therapies and small molecules as induction therapy in inflammatory bowel disease: a systematic review and meta-analysis

S Din, J Segal, J Blackwell, B Gros… - The Lancet …, 2024 - thelancet.com
Background Randomised placebo-controlled trials are the gold standard to assess novel
drugs in ulcerative colitis and Crohn's disease. However, there might be risks associated …

The historical role and contemporary use of corticosteroids in inflammatory bowel disease

AM Dorrington, CP Selinger, GC Parkes… - Journal of Crohn's …, 2020 - academic.oup.com
The use of corticosteroids to treat patients with inflammatory bowel disease [IBD] has been
the bedrock of IBD therapeutics since the pioneering work of Truelove and Witts in the UK in …

[HTML][HTML] Venous thromboembolism in inflammatory bowel disease

K Cheng, AS Faye - World journal of gastroenterology, 2020 - ncbi.nlm.nih.gov
Patients with inflammatory bowel disease (IBD) are at an increased risk for venous
thromboembolism (VTE). VTE events carry significant morbidity and mortality, and have …

[HTML][HTML] Gut dysbiosis-related thrombosis in inflammatory bowel disease: Potential disease mechanisms and emerging therapeutic strategies

A Papa, P Santini, SS De Lucia, R Maresca… - Thrombosis …, 2023 - Elsevier
Patients with inflammatory bowel disease (IBD) have an increased risk of developing
venous thromboembolic events, which have a considerable impact on morbidity and …

Does cardiovascular risk matter in IBD patients?

H Tilg, M Fumery, CRH Hedin - Journal of Internal Medicine, 2023 - Wiley Online Library
Cardiovascular and thromboembolic risks are increasing in the population as a whole and
therefore also in inflammatory bowel disease (IBD) patients. Obesity is a worldwide …

Effect of tofacitinib on cardiovascular events and all-cause mortality in patients with immune-mediated inflammatory diseases: a systematic review and meta-analysis …

W Xie, S Xiao, Y Huang, X Sun… - Therapeutic advances …, 2019 - journals.sagepub.com
Background: We aimed to systematically assess a possible association of tofacitinib therapy
with cardiovascular events (CVEs) and all-cause mortality. Methods: Systematic searches of …

[HTML][HTML] Risk of thromboembolic events and associated risk factors, including treatments, in patients with immune-mediated diseases

J Setyawan, F Mu, A Yarur, ML Zichlin, H Yang… - Clinical Therapeutics, 2021 - Elsevier
Purpose This study assessed the association between thromboembolic events (TEs) and
immune-mediated diseases (IMDs) and characterized the risk profile of TEs among patients …