Hyperhomocysteinaemia and vascular injury: advances in mechanisms and drug targets
Y Fu, X Wang, W Kong - British journal of pharmacology, 2018 - Wiley Online Library
Homocysteine is a sulphur‐containing non‐proteinogenic amino acid.
Hyperhomocysteinaemia (HHcy), the pathogenic elevation of plasma homocysteine as a …
Hyperhomocysteinaemia (HHcy), the pathogenic elevation of plasma homocysteine as a …
Does folic acid protect patients with inflammatory bowel disease from complications?
AE Ratajczak, A Szymczak-Tomczak, AM Rychter… - Nutrients, 2021 - mdpi.com
Folic acid, referred to as vitamin B9, is a water-soluble substance, which participates in the
synthesis of nucleic acids, amino acids, and proteins. Similarly to B12 and B6, vitamin B9 is …
synthesis of nucleic acids, amino acids, and proteins. Similarly to B12 and B6, vitamin B9 is …
Folate-dependent hypermobility syndrome: A proposed mechanism and diagnosis
J Courseault, C Kingry, V Morrison, C Edstrom… - Heliyon, 2023 - cell.com
Hypermobility involves excessive flexibility and systemic manifestations of connective tissue
fragility. We propose a folate-dependent hypermobility syndrome model based on clinical …
fragility. We propose a folate-dependent hypermobility syndrome model based on clinical …
Myocardial Infarction Following COVID-19 Vaccine Administration: Post Hoc, Ergo Propter Hoc?
Vaccination against coronavirus disease 2019 (COVID-19) is the safest and most effective
strategy for controlling the pandemic. However, some cases of acute cardiac events …
strategy for controlling the pandemic. However, some cases of acute cardiac events …
Association between high-dose methotrexate-induced toxicity and polymorphisms within methotrexate pathway genes in acute lymphoblastic leukemia
M Xu, S Wu, Y Wang, Y Zhao, X Wang, C Wei… - Frontiers in …, 2022 - frontiersin.org
Methotrexate (MTX) is a folic acid antagonist, the mechanism of action is to inhibit DNA
synthesis, repair and cell proliferation by decreasing the activities of several folate …
synthesis, repair and cell proliferation by decreasing the activities of several folate …
Problem in the recent American Heart association guideline on secondary stroke prevention: B vitamins to lower homocysteine do prevent stroke
In this article, we discuss a problem in the most recent American Heart Association guideline
on secondary stroke prevention that apparently arose from the rules of evidence imposed on …
on secondary stroke prevention that apparently arose from the rules of evidence imposed on …
Genetic analyses of 104 phenotypes in 20,900 Chinese pregnant women reveal pregnancy-specific discoveries
H Xiao, L Li, M Yang, X Zhang, J Zhou, J Zeng, Y Zhou… - Cell Genomics, 2024 - cell.com
Monitoring biochemical phenotypes during pregnancy is vital for maternal and fetal health,
allowing early detection and management of pregnancy-related conditions to ensure safety …
allowing early detection and management of pregnancy-related conditions to ensure safety …
Impact of MTHFR gene polymorphism on the outcome of methotrexate treatment in a sample of Iraqi rheumatoid arthritis patients
QM Mutlak, AA Kasim - Scientific Reports, 2024 - nature.com
Analyze the relationship between genetic variations in the MTHFR gene at SNPs
(rs1801131 and rs1801133) and the therapy outcomes for Iraqi patients with rheumatoid …
(rs1801131 and rs1801133) and the therapy outcomes for Iraqi patients with rheumatoid …
Associations of Maternal rs1801131 Genotype in MTHFR and Serum Folate and Vitamin B12 with Gestational Diabetes Mellitus in Chinese Pregnant Women
Circumstantial evidence links one-carbon metabolism (OCM) related nutrients, such as
folate and vitamin B12, with gestational diabetes mellitus (GDM). However, few studies have …
folate and vitamin B12, with gestational diabetes mellitus (GDM). However, few studies have …
[PDF][PDF] Folate deficiency and gene polymorphisms of MTHFR, MTR and MTRR elevate the hyperhomocysteinemia risk
We aimed to investigate the joint effect of homocysteine metabolism gene polymorphisms,
as well as the folate deficiency on the risk of HHcy in a Chinese hypertensive population …
as well as the folate deficiency on the risk of HHcy in a Chinese hypertensive population …