Rab family of small GTPases: an updated view on their regulation and functions
The Rab family of small GTPases regulates intracellular membrane trafficking by
orchestrating the biogenesis, transport, tethering, and fusion of membrane‐bound …
orchestrating the biogenesis, transport, tethering, and fusion of membrane‐bound …
Lipid droplet contact sites in health and disease
After having been disregarded for a long time as inert fat drops, lipid droplets (LDs) are now
recognized as ubiquitous cellular organelles with key functions in lipid biology and beyond …
recognized as ubiquitous cellular organelles with key functions in lipid biology and beyond …
A developmental and genetic classification for malformations of cortical development: update 2012
Malformations of cerebral cortical development include a wide range of developmental
disorders that are common causes of neurodevelopmental delay and epilepsy. In addition …
disorders that are common causes of neurodevelopmental delay and epilepsy. In addition …
Hooked! Modeling human disease in zebrafish
C Santoriello, LI Zon - The Journal of clinical investigation, 2012 - Am Soc Clin Investig
Zebrafish have been widely used as a model system for studying developmental processes,
but in the last decade, they have also emerged as a valuable system for modeling human …
but in the last decade, they have also emerged as a valuable system for modeling human …
Cellular functions of Rab GTPases at a glance
Y Zhen, H Stenmark - Journal of cell science, 2015 - journals.biologists.com
Rab GTPases control intracellular membrane traffic by recruiting specific effector proteins to
restricted membranes in a GTP-dependent manner. In this Cell Science at a Glance and the …
restricted membranes in a GTP-dependent manner. In this Cell Science at a Glance and the …
Rab18 promotes lipid droplet (LD) growth by tethering the ER to LDs through SNARE and NRZ interactions
Lipid incorporation from endoplasmic reticulum (ER) to lipid droplet (LD) is important in
controlling LD growth and intracellular lipid homeostasis. However, the molecular link …
controlling LD growth and intracellular lipid homeostasis. However, the molecular link …
Rab proteins: the key regulators of intracellular vesicle transport
T Bhuin, JK Roy - Experimental cell research, 2014 - Elsevier
Vesicular/membrane trafficking essentially regulates the compartmentalization and
abundance of proteins within the cells and contributes in many signalling pathways. This …
abundance of proteins within the cells and contributes in many signalling pathways. This …
[HTML][HTML] Toward a comprehensive map of the effectors of rab GTPases
Summary The Rab GTPases recruit peripheral membrane proteins to intracellular
organelles. These Rab effectors typically mediate the motility of organelles and vesicles and …
organelles. These Rab effectors typically mediate the motility of organelles and vesicles and …
Genomic variation in seven Khoe-San groups reveals adaptation and complex African history
The history of click-speaking Khoe-San, and African populations in general, remains poorly
understood. We genotyped∼ 2.3 million single-nucleotide polymorphisms in 220 southern …
understood. We genotyped∼ 2.3 million single-nucleotide polymorphisms in 220 southern …
Membrane trafficking in health and disease
R Yarwood, J Hellicar… - Disease models & …, 2020 - journals.biologists.com
Membrane trafficking pathways are essential for the viability and growth of cells, and play a
major role in the interaction of cells with their environment. In this At a Glance article and …
major role in the interaction of cells with their environment. In this At a Glance article and …