The addition of clopidogrel to aspirin treatment reduces ischemic events in a wide range of
patients with cardiovascular disease. However, recurrent ischemic event occurrence during …

Acute coronary syndromes (ACS) remain life-threatening disorders, which are associated
with high morbidity and mortality. Dual antiplatelet therapy with aspirin and clopidogrel has …

Pulmonary thrombosis is a significant cause of patient mortality; however, there are no
effective in vitro models of thrombi formation in human lung microvessels that could also …

Light transmission aggregometry (LTA), which was independently developed in 1962 by
Born 1 and O'Brien 2, is considered the gold standard for testing platelet function, because it …

The guideline writing group was selected to be representative of UK‐based medical experts.
MEDLINE was systematically searched for publications in English up to the Summer of 2010 …

Background Diagnosis of inherited platelet function disorders (IPFDs) is important for
appropriate management and to improve epidemiologic and clinical knowledge. However …

The vascular endothelium and shear stress are critical determinants of physiological
hemostasis and platelet function in vivo, yet current diagnostic and monitoring devices do …

Platelet function testing is important for the diagnostic evaluation of common and rare
bleeding disorders. Our study goals were to promote best practices and reduce unnecessary …

Background: Aspirin and antagonists of platelet ADP P2Y 12 receptors are often
coprescribed for protection against thrombotic events. However, blockade of platelet P2Y 12 …

The contribution of platelets to normal hemostasis and vascular disease is well described.
However, recent studies make it clear that much remains to be learned about platelet …