Role of polyphenols in combating Type 2 Diabetes and insulin resistance

M Shahwan, F Alhumaydhi, GM Ashraf… - International journal of …, 2022 - Elsevier
Compromised carbohydrate metabolism leading to hyperglycemia is the primary metabolic
disorder of non-insulin-dependent diabetes mellitus. Reformed digestion and altered …

[HTML][HTML] Future antimicrobials: Natural and functionalized phenolics

A Lobiuc, NE Pavăl, II Mangalagiu, R Gheorghiță… - Molecules, 2023 - mdpi.com
With incidence of antimicrobial resistance rising globally, there is a continuous need for
development of new antimicrobial molecules. Phenolic compounds having a versatile …

Dietary polyphenols as antidiabetic agents: Advances and opportunities

C Sun, C Zhao, EC Guven, P Paoli… - Food …, 2020 - Wiley Online Library
Dietary polyphenols have been widely investigated as antidiabetic agents in cell, animals,
human study, and clinical trial. The number of publication (Indexed by Web of Science) on …

Dietary polyphenols modulate starch digestion and glycaemic level: A review

L Sun, M Miao - Critical reviews in food science and nutrition, 2020 - Taylor & Francis
Polyphenols, as one group of secondary metabolite, are widely distributed in plants and
have been reported to show various bioactivities in recent year. Starch digestion not only is …

Inhibition mechanism of ferulic acid against α-amylase and α-glucosidase

Y Zheng, J Tian, W Yang, S Chen, D Liu, H Fang… - Food Chemistry, 2020 - Elsevier
The inhibitory mechanisms of ferulic acid against α-amylase and α-glucosidase were
investigated by enzyme kinetic analysis, circular dichroism (CD), Fourier-transform infrared …

Dietary flavonoid aglycones and their glycosides: Which show better biological significance?

J Xiao - Critical reviews in food science and nutrition, 2017 - Taylor & Francis
The dietary flavonoids, especially their glycosides, are the most vital phytochemicals in diets
and are of great general interest due to their diverse bioactivity. The natural flavonoids …

Inhibition of α-amylase by polyphenolic compounds: Substrate digestion, binding interactions and nutritional intervention

L Sun, Y Wang, M Miao - Trends in Food Science & Technology, 2020 - Elsevier
Background α-Amylase is a key enzyme of starch digestion, playing an important role in
deciding glucose releasing amount. Inhibition of the enzyme activity by polyphenols is …

Differential α-amylase/α-glucosidase inhibitory activities of plant-derived phenolic compounds: A virtual screening perspective for the treatment of obesity and diabetes

H Rasouli, SMB Hosseini-Ghazvini, H Adibi… - Food & function, 2017 - pubs.rsc.org
Recently, due to their biological properties, polyphenol-rich functional foods have been
proposed to be unique supplementary and nutraceutical treatments for diabetes mellitus …

[HTML][HTML] Flavonoids and phenolic acids from oregano: Occurrence, biological activity and health benefits

EP Gutiérrez-Grijalva, MA Picos-Salas, N Leyva-López… - Plants, 2017 - mdpi.com
Several herb species classified as oregano have been widely used in folk medicine to
alleviate inflammation-related diseases, respiratory and digestive disorders, headaches …

Natural products for glycaemic control: Polyphenols as inhibitors of alpha-amylase

L Sun, FJ Warren, MJ Gidley - Trends in Food Science & Technology, 2019 - Elsevier
Background α-Amylase plays an important role in starch digestion, the main source of
exogenous glucose in the human diet. Retarding glucose absorption through delaying …