In recent years, much attention has been paid to the assessment of the quality of health care.
This focus has been driven mainly by a desire to improve health care and decrease …

Background The endoscopic radiofrequency procedure (Stretta) has been used for more
than a decade to treat patients with gastroesophageal reflux disease (GERD). However, the …

Importance Long-term results from randomized clinical trials comparing laparoscopic sleeve
gastrectomy (LSG) with laparoscopic Roux-en-Y-gastric bypass (LRYGB) are limited …

Background Heartburn that persists despite proton-pump inhibitor (PPI) treatment is a
frequent clinical problem with multiple potential causes. Treatments for PPI-refractory …

Importance The histologic changes associated with acute gastroesophageal reflux disease
(GERD) have not been studied prospectively in humans. Recent studies in animals have …

OBJECTIVE: Laparoscopic repair of giant paraesophageal hernia is a complex operation
requiring significant laparoscopic expertise. Our objective was to compare our current …

Background Synthesis of patient-reported outcome (PRO) data is hindered by the range of
available PRO measures (PROMs) composed of multiple scales and single items with …

Background The incidence of proton pump inhibitor (PPI)-refractory gastroesophageal reflux
disease (GERD) has been increasing. While surgical intervention with Laparoscopic Nissen …

Objectives: One-and 2-year evaluation of a feasibility trial (clinicaltrials. gov registration
numbers NCT01057992, NCT01058070, and 01058564) to assess the safety and efficacy of …

BACKGROUND Fexuprazan, a novel potassium-competitive acid blocker, reversibly
suppresses the K+/H+-ATPase enzyme in proton pumps within gastric parietal cells …