[HTML][HTML] Macrophages as tools and targets in cancer therapy

A Mantovani, P Allavena, F Marchesi… - Nature Reviews Drug …, 2022 - nature.com
Tumour-associated macrophages are an essential component of the tumour
microenvironment and have a role in the orchestration of angiogenesis, extracellular matrix …

[HTML][HTML] Humoral innate immunity and acute-phase proteins

A Mantovani, C Garlanda - New England Journal of Medicine, 2023 - Mass Medical Soc
Humoral Innate Immunity and Acute-Phase Proteins | New England Journal of Medicine Skip to
main content The New England Journal of Medicine homepage Advanced Search SEARCH …

[HTML][HTML] Design of therapeutic biomaterials to control inflammation

Z Tu, Y Zhong, H Hu, D Shao, R Haag… - Nature Reviews …, 2022 - nature.com
Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …

[HTML][HTML] Interleukins in cancer: from biology to therapy

D Briukhovetska, J Dörr, S Endres, P Libby… - Nature Reviews …, 2021 - nature.com
Interleukins and associated cytokines serve as the means of communication for innate and
adaptive immune cells as well as non-immune cells and tissues. Thus, interleukins have a …

[HTML][HTML] Diverse functional autoantibodies in patients with COVID-19

EY Wang, T Mao, J Klein, Y Dai, JD Huck, JR Jaycox… - Nature, 2021 - nature.com
COVID-19 manifests with a wide spectrum of clinical phenotypes that are characterized by
exaggerated and misdirected host immune responses,,,,–. Although pathological innate …

[HTML][HTML] Inflammation-related pyroptosis, a novel programmed cell death pathway, and its crosstalk with immune therapy in cancer treatment

SK Hsu, CY Li, IL Lin, WJ Syue, YF Chen, KC Cheng… - Theranostics, 2021 - ncbi.nlm.nih.gov
In recent decades, chemotherapies targeting apoptosis have emerged and demonstrated
remarkable achievements. However, emerging evidence has shown that chemoresistance is …

[HTML][HTML] Programmed cell death tunes tumor immunity

J Liu, M Hong, Y Li, D Chen, Y Wu, Y Hu - Frontiers in immunology, 2022 - frontiersin.org
The demise of cells in various ways enables the body to clear unwanted cells. Studies over
the years revealed distinctive molecular mechanisms and functional consequences of …

Polystyrene nanoplastics toxicity to zebrafish: dysregulation of the brain–intestine–microbiota axis

M Teng, X Zhao, C Wang, C Wang, JC White, W Zhao… - ACS …, 2022 - ACS Publications
In animal species, the brain–gut axis is a complex bidirectional network between the
gastrointestinal (GI) tract and the central nervous system (CNS) consisting of numerous …

[HTML][HTML] Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

L Galluzzi, I Vitale, S Warren, S Adjemian… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune
response associated with immunological memory, provided they display sufficient …

Diversity, mechanisms, and significance of macrophage plasticity

M Locati, G Curtale, A Mantovani - Annual Review of Pathology …, 2020 - annualreviews.org
Macrophages are a diverse set of cells present in all body compartments. This diversity is
imprinted by their ontogenetic origin (embryonal versus adult bone marrow–derived cells); …