Primary cilia as dynamic and diverse signalling hubs in development and disease
Primary cilia, antenna-like sensory organelles protruding from the surface of most vertebrate
cell types, are essential for regulating signalling pathways during development and adult …
cell types, are essential for regulating signalling pathways during development and adult …
Smart materials for microrobots
Over the past 15 years, the field of microrobotics has exploded with many research groups
from around the globe contributing to numerous innovations that have led to exciting new …
from around the globe contributing to numerous innovations that have led to exciting new …
Cellular signalling by primary cilia in development, organ function and disease
Z Anvarian, K Mykytyn, S Mukhopadhyay… - Nature Reviews …, 2019 - nature.com
Primary cilia project in a single copy from the surface of most vertebrate cell types; they
detect and transmit extracellular cues to regulate diverse cellular processes during …
detect and transmit extracellular cues to regulate diverse cellular processes during …
Signaling through the primary cilium
G Wheway, L Nazlamova, JT Hancock - Frontiers in cell and …, 2018 - frontiersin.org
The presence of single, non-motile “primary” cilia on the surface of epithelial cells has been
well described since the 1960s. However, for decades these organelles were believed to be …
well described since the 1960s. However, for decades these organelles were believed to be …
Spatially resolved transcriptomics reveals the architecture of the tumor-microenvironment interface
During tumor progression, cancer cells come into contact with various non-tumor cell types,
but it is unclear how tumors adapt to these new environments. Here, we integrate spatially …
but it is unclear how tumors adapt to these new environments. Here, we integrate spatially …
The primary cilium: a signalling centre during vertebrate development
SC Goetz, KV Anderson - Nature Reviews Genetics, 2010 - nature.com
The primary cilium has recently stepped into the spotlight, as a flood of data show that this
organelle has crucial roles in vertebrate development and human genetic diseases. Cilia …
organelle has crucial roles in vertebrate development and human genetic diseases. Cilia …
Cilium structure, assembly, and disassembly regulated by the cytoskeleton
The cilium, once considered a vestigial structure, is a conserved, microtubule-based
organelle critical for transducing extracellular chemical and mechanical signals that control …
organelle critical for transducing extracellular chemical and mechanical signals that control …
[HTML][HTML] Pay attention to membrane tension: Mechanobiology of the cell surface
E Sitarska, A Diz-Muñoz - Current opinion in cell biology, 2020 - Elsevier
The cell surface is a mechanobiological unit that encompasses the plasma membrane, its
interacting proteins, and the complex underlying cytoskeleton. Recently, attention has been …
interacting proteins, and the complex underlying cytoskeleton. Recently, attention has been …
Role of ion channels and transporters in cell migration
A Schwab, A Fabian, PJ Hanley… - Physiological …, 2012 - journals.physiology.org
Cell motility is central to tissue homeostasis in health and disease, and there is hardly any
cell in the body that is not motile at a given point in its life cycle. Important physiological …
cell in the body that is not motile at a given point in its life cycle. Important physiological …
The primary cilium at a glance
P Satir, LB Pedersen… - Journal of cell …, 2010 - journals.biologists.com
The primary cilium, which was first so named by Sergei Sorokin (Sorokin, 1968), is a solitary
organelle that emanates from the cell surface of most mammalian cell types during growth …
organelle that emanates from the cell surface of most mammalian cell types during growth …