The origin of animal multicellularity and cell differentiation

T Brunet, N King - Developmental cell, 2017 - cell.com
Over 600 million years ago, animals evolved from a unicellular or colonial organism whose
cell (s) captured bacteria with a collar complex, a flagellum surrounded by a microvillar …

The origin of Metazoa: a unicellular perspective

A Sebé-Pedrós, BM Degnan, I Ruiz-Trillo - Nature Reviews Genetics, 2017 - nature.com
The first animals evolved from an unknown single-celled ancestor in the Precambrian
period. Recently, the identification and characterization of the genomic and cellular traits of …

Early metazoan cell type diversity and the evolution of multicellular gene regulation

A Sebé-Pedrós, E Chomsky, K Pang… - Nature ecology & …, 2018 - nature.com
A hallmark of metazoan evolution is the emergence of genomic mechanisms that implement
cell-type-specific functions. However, the evolution of metazoan cell types and their …

The origin of animals: an ancestral reconstruction of the unicellular-to-multicellular transition

N Ros-Rocher, A Pérez-Posada, MM Leger… - Open …, 2021 - royalsocietypublishing.org
How animals evolved from a single-celled ancestor, transitioning from a unicellular lifestyle
to a coordinated multicellular entity, remains a fascinating question. Key events in this …

The origin of metazoan multicellularity: a potential microbial black swan event

I Ruiz-Trillo, K Kin, E Casacuberta - Annual Review of …, 2023 - annualreviews.org
The emergence of animals from their unicellular ancestors is a major evolutionary event.
Thanks to the study of diverse close unicellular relatives of animals, we now have a better …

Gene family innovation, conservation and loss on the animal stem lineage

DJ Richter, P Fozouni, MB Eisen, N King - elife, 2018 - elifesciences.org
Choanoflagellates, the closest living relatives of animals, can provide unique insights into
the changes in gene content that preceded the origin of animals. However, only two …

Dynamics of genomic innovation in the unicellular ancestry of animals

X Grau-Bove, G Torruella, S Donachie, H Suga… - Elife, 2017 - elifesciences.org
Which genomic innovations underpinned the origin of multicellular animals is still an open
debate. Here, we investigate this question by reconstructing the genome architecture and …

Genomic adaptations to aquatic and aerial life in mayflies and the origin of insect wings

I Almudi, J Vizueta, CDR Wyatt, A de Mendoza… - Nature …, 2020 - nature.com
The evolution of winged insects revolutionized terrestrial ecosystems and led to the largest
animal radiation on Earth. However, we still have an incomplete picture of the genomic …

Proteotype coevolution and quantitative diversity across 11 mammalian species

Q Ba, Y Hei, A Dighe, W Li, J Maziarz, I Pak… - Science …, 2022 - science.org
Evolutionary profiling has been largely limited to the nucleotide level. Using consistent
proteomic methods, we quantified proteomic and phosphoproteomic layers in fibroblasts …

Chemical factors induce aggregative multicellularity in a close unicellular relative of animals

N Ros-Rocher, RQ Kidner, C Gerdt… - Proceedings of the …, 2023 - National Acad Sciences
Regulated cellular aggregation is an essential process for development and healing in
many animal tissues. In some animals and a few distantly related unicellular species …