Abstract N 6-Methyladenosine (m6A), the most abundant internal modification associated
with eukaryotic mRNAs, has emerged as a dynamic regulatory mechanism controlling the …

Gamete abnormalities and reproductive system tumors have become a dominant cause of
infertility, troubling people globally. In recent years, increasing evidence emerged and found …

It is urgent and important to understand the relationship of the widespread severe acute
respiratory syndrome coronavirus clade 2 (SARS-CoV-2) with host immune response and …

Abstract N 6-methyladenosine (m6A) is the most prevalent modification of messenger RNA
in mammals. To interrogate its functions and dynamics, there is a critical need to quantify …

Abstract N 6-methyladenosine (m 6 A) is an abundant internal RNA modification, influencing
transcript fate and function in uninfected and virus-infected cells. Installation of m 6 A by the …

Splicing of precursor mRNAs (pre-mRNA) is an important step during eukaryotic gene
expression. The identification of the actual splice sites and the proper removal of introns are …

Adenovirus is a nuclear replicating DNA virus reliant on host RNA processing machinery.
Processing and metabolism of cellular RNAs can be regulated by METTL3, which catalyzes …

Many cellular mRNAs contain the modified base m6A, and recent studies have suggested
that various stimuli can lead to changes in m6A. The most common method to map m6A and …

Excessive cytokine activity underlies many autoimmune conditions, particularly through the
interleukin-17 (IL-17) and tumor necrosis factor–α (TNFα) signaling axis. Both cytokines …

Cells have evolved highly specialized sentinels that detect viral infection and elicit an
antiviral response. Among these, the stress-sensing protein kinase R, which is activated by …