MUC1 and MUC16: critical for immune modulation in cancer therapeutics
X Chen, IK Sandrine, M Yang, J Tu, X Yuan - Frontiers in immunology, 2024 - frontiersin.org
The Mucin (MUC) family, a range of highly glycosylated macromolecules, is ubiquitously
expressed in mammalian epithelial cells. Such molecules are pivotal in establishing …
expressed in mammalian epithelial cells. Such molecules are pivotal in establishing …
Sindbis Virus Vaccine Platform: A Promising Oncolytic Virus-Mediated Approach for Ovarian Cancer Treatment
C Pampeno, S Opp, A Hurtado, D Meruelo - International Journal of …, 2024 - mdpi.com
This review article provides a comprehensive overview of a novel Sindbis virus vaccine
platform as potential immunotherapy for ovarian cancer patients. Ovarian cancer is the most …
platform as potential immunotherapy for ovarian cancer patients. Ovarian cancer is the most …
Targeting mucin protein enables rapid and efficient ovarian cancer cell capture: role of nanoparticle properties in efficient capture and culture
N Feely, A Wdowicz, A Chevalier, Y Wang, P Li, F Rollo… - Small, 2023 - Wiley Online Library
The development of specific and sensitive immunomagnetic cell separation
nanotechnologies is central to enhancing the diagnostic relevance of circulating tumor cells …
nanotechnologies is central to enhancing the diagnostic relevance of circulating tumor cells …
Development of triple-negative breast cancer-targeted liposomes with MUC16 binding peptide ligand in triple-negative breast cancer cells
M Hagimori, N Kato, A Orimoto, T Suga… - Journal of …, 2023 - Elsevier
Triple-negative breast cancer (TNBC) is a highly malignant tumor that does not express the
estrogen receptor (ER), progesterone receptor (PR), or human epidermal growth factor …
estrogen receptor (ER), progesterone receptor (PR), or human epidermal growth factor …
MUC16: clinical targets with great potential
XY Zhang, LL Hong, Z Ling - Clinical and Experimental Medicine, 2024 - Springer
Abstract Mucin 16 (MUC16) is a membrane-bound mucin that is abnormally expressed or
mutated in a variety of diseases, especially tumors, while being expressed in normal body …
mutated in a variety of diseases, especially tumors, while being expressed in normal body …
Biomarkers or biotargets? Using competition to lure cancer cells into evolutionary traps
Abstract Background and Objectives Cancer biomarkers provide information on the
characteristics and extent of cancer progression and help inform clinical decision-making …
characteristics and extent of cancer progression and help inform clinical decision-making …
[HTML][HTML] Current status and research progress of oncolytic virus
Y Chen, M Tao, X Wu, Z Tang, Y Zhu, K Gong… - Pharmaceutical Science …, 2024 - Elsevier
Oncolytic viruses (OVs) are natural or genetically recombinant viruses that selectively infect
and kill tumor cells without affecting normal cell growth. As a novel type of immunotherapy …
and kill tumor cells without affecting normal cell growth. As a novel type of immunotherapy …
A revised molecular model of ovarian cancer biomarker CA125 (MUC16) enabled by long-read sequencing
CW Wang, SD Weaver, N Boonpattrawong… - Cancer Research …, 2024 - AACR
The biomarker CA125, a peptide epitope located in several tandem repeats of the mucin
MUC16, is the gold standard for monitoring regression and recurrence of high-grade serous …
MUC16, is the gold standard for monitoring regression and recurrence of high-grade serous …
Research Advances of Clinical Application of Oncolytic Viruses in Treatment of Gynecologic Cancers
M Deng, Q Wang - Current Cancer Drug Targets, 2023 - ingentaconnect.com
Oncolytic viruses (OVs) have become one of the main strategies of cancer biotherapy. They
are genetically engineered or naturally occurring viruses that selectively replicate and kill …
are genetically engineered or naturally occurring viruses that selectively replicate and kill …