Use of mucolytics and inhaled antibiotics in the NICU

AI Gipsman, A Bhandari, V Bhandari - Journal of Perinatology, 2024 - nature.com
Clearance of airway secretions and treatment of respiratory tract infections (RTIs) are two
common problems caregivers face in the neonatal intensive care unit (NICU). Mucolytics …

Influence of catheter thickness on respiratory physiology during less invasive surfactant administration in extremely preterm infants

CC Gunatilaka, Q Xiao, AJ Bates, AR Franz… - Frontiers in …, 2024 - frontiersin.org
Introduction Delivering surfactant via thin catheters (minimal-invasive surfactant therapy
(MIST); less invasive surfactant administration (LISA)) has become a common procedure …

The effect of including dynamic imaging derived airway wall motion in CFD simulations of respiratory airflow in patients with OSA

Q Xiao, C Gunatilaka, K McConnell, A Bates - Scientific Reports, 2024 - nature.com
Obstructive sleep apnea (OSA) is an airway disease caused by periodic collapse of the
airway during sleep. Imaging-based subject-specific computational fluid dynamics (CFD) …

Effect of airway wall motion on particle deposition and delivery in the neonatal trachea

CC Gunatilaka, C McKenzie, Q Xiao, NS Higano… - Journal of Aerosol …, 2024 - Elsevier
Modeling pulmonary drug delivery in the airway using computational fluid dynamics (CFD)
simulations tracks drug particles throughout the airway, providing valuable information on …

Effects of decongestion on nasal cavity air conditioning efficiency: a CFD cohort study

Q Xiao, AJ Bates, DJ Doorly - Scientific Reports, 2024 - nature.com
Decongestion reduces blood flow in the nasal turbinates, enlarging the airway lumen.
Although the enlarged airspace reduces the trans-nasal inspiratory pressure drop …