Novel syntheses of azetidines and azetidinones

A Brandi, S Cicchi, FM Cordero - Chemical Reviews, 2008 - ACS Publications
Four-membered monocyclic aza-heterocycles, 1 despite their indisputable importance as
bioactive compounds and pharmaceutical tools, have received by the chemical community …

Recent developments in the stereoselective synthesis of α-aminoacids

RO Duthaler - Tetrahedron, 1994 - Elsevier
The a-amino-carboxylic-acids are one of the five major classes of natural products and they
exhibit.-important and diverse biological functions.',* Historically, the aminoacids have been …

The Chemistry of Azetidin-3-ones, Oxetan-3-ones, and Thietan-3-ones

Y Dejaegher, NM Kuz'menok, AM Zvonok… - Chemical …, 2002 - ACS Publications
The aim of this review is to cover the literature of 3-azetidinones, 3-oxetanones, and 3-
thietanones, including partially 3-thietanone-1-oxides and 3-thietanone-1, 1-dioxides. Each …

Conformationally rigid cyclic α-amino acids in the design of peptidomimetics, peptide models and biologically active compounds

IV Komarov, AO Grigorenko, AV Turov… - Russian chemical …, 2004 - pubs.rsc.org
A class of conformationally rigid cyclic α-amino acids that can be used in the synthesis of
peptidomimetics, peptide models and biologically active compounds is surveyed. The rigid …

Total Synthesis of Aigialomycin D using a One-Pot Ketene Generation− Trapping− Aromatization Sequence

F Calo, J Richardson, AGM Barrett - Organic Letters, 2009 - ACS Publications
Total Synthesis of Aigialomycin D using a One-Pot Ketene Generation−Trapping−Aromatization
Sequence | Organic Letters ACS ACS Publications C&EN CAS Find my institution Log In …

Enantioselective Copper‐Catalyzed Intramolecular N− H Bond Insertion: Synthesis of Chiral 2‐Carboxytetrahydroquinolines

XG Song, YY Ren, SF Zhu… - Advanced Synthesis & …, 2016 - Wiley Online Library
The first highly enantioselective intramolecular N− H bond insertion was realized by using
copper catalysts modified with chiral spirobisoxazoline ligands, which provides a novel …

N–H insertion reactions of rhodium carbenoids. Part 1. Preparation of α-amino acid and α-aminophosphonic acid derivatives

J BobbyáSanghera - Journal of the Chemical Society, Perkin …, 1996 - pubs.rsc.org
Rhodium (II) acetate-catalysed decomposition of diazophenylacetates 1 and 3 in the
presence of a range of N–H compounds results in an N–H insertion reaction of the …

Synthesis of chiral non racemic azetidines

F Couty, G Evano, D Prim - Mini-Reviews in Organic Chemistry, 2004 - benthamdirect.com
Synthesis of Chiral Non Racemic Azetidines Page 1 Mini-Reviews in Organic Chemistry, 2004,
1, 133-148 133 1570-193X/04 $45.00+.00 © 2004 Bentham Science Publishers Ltd. Synthesis …

Metal carbene N–H insertion of chiral α, α′-dialkyl α-diazoketones. A novel and concise method for the stereocontrolled synthesis of fully substituted azetidines

ACB Burtoloso, CRD Correia - Tetrahedron letters, 2004 - Elsevier
The syntheses of all cis substituted azetidines were accomplished in few steps from l-serine
in modest to high yields. The key step was based on a rhodium or copper carbenoid N–H …

Azetidin‐3‐ones from (S)‐α‐Amino Acids and Their Reactions with Nucleophiles: Preparation of some azetidine‐containing amino‐alcohol and amino‐acid …

J Podlech, D Seebach - Helvetica chimica acta, 1995 - Wiley Online Library
The reactions of azetidin‐3‐ones 6–10, readily available from the amino acids l‐alanine, l‐
phenylalanine, l‐valine, l‐lysine, and l‐aspartic acid, via the corresponding diazo ketones …