Brain circuitry of compulsivity

OA Van den Heuvel, G van Wingen… - European …, 2016 - Elsevier
Compulsivity is associated with alterations in the structure and the function of parallel and
interacting brain circuits involved in emotional processing (involving both the reward and the …

Diffusion imaging, white matter, and psychopathology

ME Thomason, PM Thompson - Annual review of clinical …, 2011 - annualreviews.org
The functional significance of the brain's white matter was not fully appreciated until new
imaging methods were developed to visualize fiber pathways and connections in the living …

The major symptom dimensions of obsessive-compulsive disorder are mediated by partially distinct neural systems

OA Van Den Heuvel, PL Remijnse, D Mataix-Cols… - Brain, 2009 - academic.oup.com
Obsessive–compulsive disorder (OCD) is a clinically heterogeneous disorder characterized
by multiple, temporally stable symptom dimensions. Preliminary functional neuroimaging …

A systematic review of diffusion tensor imaging studies in affective disorders

CE Sexton, CE Mackay, KP Ebmeier - Biological psychiatry, 2009 - Elsevier
White matter abnormalities constitute one element of the network dysfunction that underlies
affective disorders: differences between the white matter of subjects with affective disorders …

Microstructural brain abnormalities in medication-free patients with major depressive disorder: a systematic review and meta-analysis of diffusion tensor imaging

J Jiang, YJ Zhao, XY Hu, MY Du, ZQ Chen, M Wu… - Journal of Psychiatry and …, 2017 - jpn.ca
Background: Multiple meta-analyses of diffusion tensor imaging (DTI) studies have reported
impaired white matter integrity in patients with major depressive disorder (MDD). However …

[HTML][HTML] Shared white matter alterations across emotional disorders: a voxel-based meta-analysis of fractional anisotropy

LM Jenkins, A Barba, M Campbell, M Lamar… - NeuroImage: Clinical, 2016 - Elsevier
Background White matter (WM) integrity may represent a shared biomarker for emotional
disorders (ED). Aims: To identify transdiagnostic biomarkers of reduced WM by meta …

Meta-analytic investigations of structural grey matter, executive domain-related functional activations, and white matter diffusivity in obsessive compulsive disorder: an …

GK Eng, K Sim, SHA Chen - Neuroscience & Biobehavioral Reviews, 2015 - Elsevier
Obsessive–compulsive disorder (OCD) is a debilitating disorder. However, existing
neuroimaging findings involving executive function and structural abnormalities in OCD …

Major depressive disorder and white matter abnormalities: a diffusion tensor imaging study with tract-based spatial statistics

T Kieseppä, M Eerola, R Mäntylä, T Neuvonen… - Journal of affective …, 2010 - Elsevier
BACKGROUND: A few diffusion tensor imaging (DTI) studies have shown abnormalities in
areas of white matter tracts involved in mood regulation in geriatric depressive patients …

Changes in gray matter volume and white matter microstructure in adolescents with obsessive-compulsive disorder

M Zarei, D Mataix-Cols, I Heyman, M Hough… - Biological …, 2011 - Elsevier
BACKGROUND: There is a paucity of neuroimaging data in pediatric-onset obsessive-
compulsive disorder (OCD). This multimodal neuroimaging study aimed to identify structural …

Diffusion tensor imaging (DTI) studies in patients with obsessive-compulsive disorder (OCD): a review

K Koch, TJ Reeß, OG Rus, C Zimmer… - Journal of psychiatric …, 2014 - Elsevier
This review presents an overview of studies investigating white-matter integrity in patients
with obsessive-compulsive disorder (OCD) using diffusion tensor imaging (DTI). There is …