Bridging animal and human models of exercise-induced brain plasticity

MW Voss, C Vivar, AF Kramer, H van Praag - Trends in cognitive sciences, 2013 - cell.com
Significant progress has been made in understanding the neurobiological mechanisms
through which exercise protects and restores the brain. In this feature review, we integrate …

The neuroprotective effects of exercise: maintaining a healthy brain throughout aging

LM Vecchio, Y Meng, K Xhima, N Lipsman… - Brain …, 2018 - content.iospress.com
Physical activity plays an essential role in maintaining a healthy body, yet it also provides
unique benefits for the vascular and cellular systems that sustain a healthy brain. While the …

Lactate mediates the effects of exercise on learning and memory through SIRT1-dependent activation of hippocampal brain-derived neurotrophic factor (BDNF)

L El Hayek, M Khalifeh, V Zibara… - Journal of …, 2019 - Soc Neuroscience
Exercise promotes learning and memory formation. These effects depend on increases in
hippocampal BDNF, a growth factor associated with cognitive improvement and the …

Exercise-enhanced neuroplasticity targeting motor and cognitive circuitry in Parkinson's disease

GM Petzinger, BE Fisher, S McEwen, JA Beeler… - The Lancet …, 2013 - thelancet.com
Exercise interventions in individuals with Parkinson's disease incorporate goal-based motor
skill training to engage cognitive circuitry important in motor learning. With this exercise …

Lifestyle modulators of neuroplasticity: how physical activity, mental engagement, and diet promote cognitive health during aging

C Phillips - Neural plasticity, 2017 - Wiley Online Library
The number of the elderly across the globe will approximate 2.1 billion by 2050. Juxtaposed
against this burgeoning segment of the population is evidence that nonpathological aging is …

[HTML][HTML] The influence of exercise on cognitive abilities

F Gomez-Pinilla, C Hillman - Comprehensive Physiology, 2013 - ncbi.nlm.nih.gov
Scientific evidence based on neuroimaging approaches over the last decade has
demonstrated the efficacy of physical activity improving cognitive health across the human …

Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging

JE Ahlskog, YE Geda, NR Graff-Radford… - Mayo clinic …, 2011 - Elsevier
A rapidly growing literature strongly suggests that exercise, specifically aerobic exercise,
may attenuate cognitive impairment and reduce dementia risk. We used PubMed (keywords …

The effects of cardiovascular exercise on human memory: a review with meta-analysis

M Roig, S Nordbrandt, SS Geertsen… - … & Biobehavioral Reviews, 2013 - Elsevier
We reviewed the evidence for the use of cardiovascular exercise to improve memory and
explored potential mechanisms. Data from 29 and 21 studies including acute and long-term …

Molecular and cellular pathways contributing to brain aging

A Zia, AM Pourbagher-Shahri, T Farkhondeh… - Behavioral and Brain …, 2021 - Springer
Aging is the leading risk factor for several age-associated diseases such as
neurodegenerative diseases. Understanding the biology of aging mechanisms is essential …

Acute exercise improves motor memory: exploring potential biomarkers

K Skriver, M Roig, J Lundbye-Jensen, J Pingel… - Neurobiology of learning …, 2014 - Elsevier
We have recently shown that a single bout of acute cardiovascular exercise improves motor
skill learning through an optimization of long-term motor memory. Here we expand this …