Diversity and evolution of the animal virome

E Harvey, EC Holmes - Nature Reviews Microbiology, 2022 - nature.com
The COVID-19 pandemic has given the study of virus evolution and ecology new relevance.
Although viruses were first identified more than a century ago, we likely know less about …

Glycoinformatics in the artificial intelligence era

D Bojar, F Lisacek - Chemical Reviews, 2022 - ACS Publications
Artificial intelligence (AI) methods have been and are now being increasingly integrated in
prediction software implemented in bioinformatics and its glycoscience branch known as …

Identification of mobile genetic elements with geNomad

AP Camargo, S Roux, F Schulz, M Babinski, Y Xu… - Nature …, 2024 - nature.com
Identifying and characterizing mobile genetic elements in sequencing data is essential for
understanding their diversity, ecology, biotechnological applications and impact on public …

IMG/VR v4: an expanded database of uncultivated virus genomes within a framework of extensive functional, taxonomic, and ecological metadata

AP Camargo, S Nayfach, IMA Chen… - Nucleic acids …, 2023 - academic.oup.com
Viruses are widely recognized as critical members of all microbiomes. Metagenomics
enables large-scale exploration of the global virosphere, progressively revealing the …

[HTML][HTML] Expansion of the global RNA virome reveals diverse clades of bacteriophages

U Neri, YI Wolf, S Roux, AP Camargo, B Lee… - Cell, 2022 - cell.com
High-throughput RNA sequencing offers broad opportunities to explore the Earth RNA
virome. Mining 5,150 diverse metatranscriptomes uncovered> 2.5 million RNA virus contigs …

Twenty-five years of Genomes OnLine Database (GOLD): data updates and new features in v. 9

S Mukherjee, D Stamatis, CT Li… - Nucleic acids …, 2023 - academic.oup.com
Abstract The Genomes OnLine Database (GOLD)(https://gold. jgi. doe. gov/) at the
Department of Energy Joint Genome Institute (DOE-JGI) continues to maintain its role as one …

Hybrids of RNA viruses and viroid-like elements replicate in fungi

M Forgia, B Navarro, S Daghino, A Cervera… - Nature …, 2023 - nature.com
Earth's life may have originated as self-replicating RNA, and it has been argued that RNA
viruses and viroid-like elements are remnants of such pre-cellular RNA world. RNA viruses …

High-quality metagenome assembly from long accurate reads with metaMDBG

G Benoit, S Raguideau, R James, AM Phillippy… - Nature …, 2024 - nature.com
We introduce metaMDBG, a metagenomics assembler for PacBio HiFi reads. MetaMDBG
combines a de Bruijn graph assembly in a minimizer space with an iterative assembly over …

Minimizer-space de Bruijn graphs: Whole-genome assembly of long reads in minutes on a personal computer

B Ekim, B Berger, R Chikhi - Cell systems, 2021 - cell.com
DNA sequencing data continue to progress toward longer reads with increasingly lower
sequencing error rates. Here, we define an algorithmic approach, mdBG, that makes use of …

Viruses defined by the position of the virosphere within the replicator space

EV Koonin, VV Dolja, M Krupovic… - … and Molecular Biology …, 2021 - Am Soc Microbiol
Originally, viruses were defined as miniscule infectious agents that passed through filters
that retain even the smallest cells. Subsequently, viruses were considered obligate …