Platelet microparticles: detection and assessment of their paradoxical functional roles in disease and regenerative medicine

T Burnouf, HA Goubran, ML Chou, D Devos… - Blood reviews, 2014 - Elsevier
There is increasing research on and clinical interest in the physiological role played by
platelet microparticles (PMPs). PMPs are 0.1–1-μm fragments shed from plasma …

Extracellular vesicles and asthma—More than just a co-existence

B Alashkar Alhamwe, DP Potaczek, S Miethe… - International journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) are membranous structures, which are secreted by almost every
cell type analyzed so far. In addition to their importance for cell-cell communication under …

Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets

A Pienimaeki‐Roemer, K Kuhlmann, A Böttcher… - …, 2015 - Wiley Online Library
Background Platelets (PLT s) in stored PLT concentrates (PLC s) release PLT extracellular
vesicles (PL‐EV s) induced by senescence and activation, resembling the PLT storage …

The role of platelet-derived extracellular vesicles in immune-mediated thrombosis

AS Eustes, S Dayal - International journal of molecular sciences, 2022 - mdpi.com
Platelet-derived extracellular vesicles (PEVs) play important roles in hemostasis and
thrombosis. There are three major types of PEVs described based on their size and …

Blood-based biomarkers for eosinophilic esophagitis and concomitant atopic diseases: a look into the potential of extracellular vesicles

E Grueso-Navarro, P Navarro… - International Journal of …, 2023 - mdpi.com
Eosinophilic esophagitis (EoE) is a chronic, Th2-inflammatory disease of the esophagus that
can severely affect food intake. Currently, diagnosis and assessing response to treatment of …

[HTML][HTML] Extracellular vesicles in lung health, disease, and therapy

MJ McVey, M Maishan, KEC Blokland… - … of Physiology-Lung …, 2019 - journals.physiology.org
Both physiological homeostasis and pathological disease processes in the lung typically
result from complex, yet coordinated multicellular responses that are synchronized via …

Characterization and origins of cell-free mitochondria in healthy murine and human blood

OR Stephens, D Grant, M Frimel, N Wanner, M Yin… - Mitochondrion, 2020 - Elsevier
Intact cell-free mitochondria have been reported in microparticles (MPs) in murine and
human bodily fluids under disease conditions. However, cellular origins of circulating …

Possible roles of platelet-derived microparticles in atherosclerosis

ZT Wang, Z Wang, YW Hu - Atherosclerosis, 2016 - Elsevier
Platelets and platelet-derived microparticles (PMPs) play important roles in cardiovascular
diseases, especially atherosclerosis. Continued research has revealed that PMPs have …

Platelet‐derived microparticles promote endothelial cell proliferation in hypertension via miR‐142–3p

H Bao, YX Chen, K Huang, F Zhuang, M Bao… - The FASEB …, 2018 - Wiley Online Library
Endothelial cells (ECs) are located at the interface between flowing blood and the vessel
wall, and abnormal EC proliferation induced by pathologic environments plays an important …

[PDF][PDF] Role of extracellular vesicles in chronic lung disease

A Trappe, SC Donnelly, P McNally, JA Coppinger - Thorax, 2021 - thorax.bmj.com
To explore the role of extracellular vesicles (EVs) in chronic lung diseases. EVs are
emerging as mediators of intercellular communication and possible diagnostic markers of …